Results 101 to 110 of about 5,709,157 (253)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Nutrition health promotion: framework for action.
Optimal health for Irish people can only be achieved when greater efforts are made towards health promotion and prevention of illness and when nutrition is an integral part of these efforts.
Department of Health (DoH). Health Promotion Unit
core
Whole-school mental health promotion in Australia [PDF]
Although there is increasing recognition internationally of the significance of social and emotional health and wellbeing for the healthy development of young people, the levels of support that governments provide for mental health policy and programme ...
Slee, Phillip T. +7 more
core +1 more source
The communication of social norms is a strong driver of behavior and is therefore recommended as a persuasive tool for tax compliance. However, the evidence on the influence of social norms on tax behavior remains inconclusive. Ambiguous results could be
Janet Kleber +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Effectively planning, implementing, and evaluating health promotion programs can promote behavioral and social change, contribute to the elimination of health inequalities, and improve health outcomes.
core
This study investigates the relationship among job attitudes (job satisfaction and turnover intentions), heavy work investment (work engagement and workaholism), and work motivation (promotion focus and prevention focus).
Ishfaq Ahmed, Muhammad Khalid Khan
doaj
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source

