Results 231 to 240 of about 1,398,017 (305)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Connotation and Mechanism of Family Support for Patients with Chronic Diseases Under the Perspective of Health Promotion-A Scoping Review of Reviews. [PDF]

J Multidiscip Healthc
Li J, Cheng L, Tu L, Wang X, Wei Y, Shen F, Wang J, Chen B.   +7 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Assessing entrepreneurial transformation in agricultural universities using hybrid multi-criteria decision-making. [PDF]

Sci Rep
Far ST, Rezaei-Moghaddam K, Zibaei M, Dallago B.   +3 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Mapping the type, frequency, intensity, temporality, and pathways of dissemination strategies during the national scale-up of TransformUs Secondary. [PDF]

Transl Behav Med
Fitriani A, Koorts H, Contardo Ayala AM, Lander N, Orr J, Martin-Alcaide N, Salmon J.   +6 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Editorial: Cellular replacement therapy for diabetes. [PDF]

Cell Transplant
Sakata N, Yoshimatsu G, Kodama S.
europepmc   +1 more source

Reforming schools into health promoting schools: perspective based on expert consensus from a European multistakeholder consultation. [PDF]

Eur J Pediatr
Makris KC, Philippou C, Vasileiou C, Tornaritis M, Michaelidou SC, Hadjigeorgiou C, Kyriacou M, Santamouris M, Grotto I, Bose-O'Reilly S, Breda J, van den Hazel P.   +11 more
europepmc   +1 more source

Children's and youth mental health in all policies?: a document analysis. [PDF]

BMC Public Health
Fjellfeldt M, Eriksson C.
europepmc   +1 more source