Results 201 to 210 of about 4,804,928 (276)

Prompt Engineering Accelerates the Data-Driven Discovery of Photocatalysts via an LLM-Based Model Ensemble Strategy. [PDF]

Adv Sci (Weinh)
Li D, Sun X, Sun S, Wang R, Zhang M, Xiao M, Wang Y, Zhang Y.   +7 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Prompt engineering competence, knowledge management, and technology fit as drivers of educational sustainability through generative AI. [PDF]

Sci Rep
Gibreel O, Karataş K, Arpaci I.
europepmc   +1 more source

Engineering Prompts for Spatial Questions

Companion Proceedings of the ACM on Web Conference 2025
Nicole R. Schneider, Nandini Ramachandran, Kent O'Sullivan, Hanan Samet   +3 more
openaire   +2 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Guidelines vs. generative AI in CKD patient education: the role of prompt engineering and expert blinded evaluation. [PDF]

BMC Nephrol
Koc LZ, Gulsen Koc S, Inci A, Buldukoglu OC, Koker G, Lerma EV.   +5 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Individual Segmentation of Intertwined Apple Trees in a Row via Prompt Engineering. [PDF]

Sensors (Basel)
Metuarea H, Laurens F, Guerra W, Lozano L, Patocchi A, Van Hoye S, Dutagaci H, Labrosse J, Rasti P, Rousseau D.   +9 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Deficiencies in clinical reasoning of LLMs in low back pain management and remediation via prompt engineering: from performance evaluation to error diagnosis. [PDF]

Front Artif Intell
Luo JH, Wang YL, Zhao MJ, Yin JL, Ding DF, Wu XB.   +5 more
europepmc   +1 more source