Results 91 to 100 of about 594,829 (295)
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Characterizing Periodic Messaging Interventions Across Health Behaviors and Media: Systematic Review
Journal of Medical Internet Research, 2014 BackgroundPeriodic prompts serve as tools for health behavior interventions to encourage and maintain behavior changes. Past literature reviews have examined periodic messages targeting specific behaviors (smoking, physical activity, diet, etc) or media (
De Leon, Elaine +2 more
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Profile: Issues in Teachers' Professional Development, 2008 Motivated by the conviction that valid and reliable assessments can foster positive changes in instruction, we implemented a writing assessment system in the adult English program at the Language Center, EAFIT University, Medellín. To evaluate the impact
Ana Patricia Muñoz, Martha E Álvarez
doaj
Impressionistic techniques applied in sound art & design [PDF]
, 2018 Sound art and design collectively refer to the process of specifying, acquiring, manipulating or generating sonic elements to evoke emotion and environment.
Sapp, Kaitlyn E. M.
core
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Automatic Optimization and Evaluation of Prompt Fairness Based on Large Language Model Itself [PDF]
Jisuanji kexueWith the rapid development of large language models,the issue of model fairness has garnered increasing attention,primarily focusing on biases in generated text and downstream tasks.To produce fairer text,careful design and examination of the fairness of
ZHU Shucheng, HUO Hongying, WANG Weikang, LIU Ying, LIU Pengyuan
doaj +1 more source
Early literacy support programme : top-up session materials for teaching assistants [PDF]
, 2002 These sessions are designed to provide extra support for children who have been included in the ELS Programme and assessed through the ELS ‘Exit Strategy’ (see ELS Book p.
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source