Results 51 to 60 of about 1,036,863 (338)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Prone Versus Sitting Position in Neurosurgery-Differences in Patients' Hemodynamic Management [PDF]

open access: yes, 2017
OBJECTIVE: Neurosurgery in general anesthesia exposes patients to hemodynamic alterations in both the prone and the sitting position. We aimed to evaluate the hemodynamic profile during stroke volume-directed fluid administration in patients undergoing ...
Hernesniemi, Juha   +7 more
core   +1 more source

Treatment of ARDS With Prone Positioning [PDF]

open access: yesChest, 2017
Prone positioning was first proposed in the 1970s as a method to improve gas exchange in ARDS. Subsequent observations of dramatic improvement in oxygenation with simple patient rotation motivated the next several decades of research. This work elucidated the physiological mechanisms underlying changes in gas exchange and respiratory mechanics with ...
Scholten, Eric L   +3 more
openaire   +4 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Obturator Nerve Palsy in a Patient with Fascio Scapulo Humeral Dystrophy Undergoing Scapulopexy in Prone Position: A Rare Occurrence [PDF]

open access: yesActa Medica Iranica, 2009
All surgical positions carry some degree of position-related risks. The most common serious positional injuries are peripheral nerve injuries. We present a case of 23 years old man with obturator nerve injury with clinically evident sequelae following a ...
Hussain Khan Zahid   +2 more
doaj   +2 more sources

Prone position and APRV for severe hypoxemia in COVID-19 patients: The role of perfusion

open access: yesJournal of Mechanical Ventilation, 2020
There have been confusion and contradiction on how to best manage patients with acute respiratory failure secondary to Corona virus disease-2019 (COVID-19). Recent report suggested two different phenotypes of patho-physiology (type L and type H).
Ehab G. Daoud   +2 more
doaj   +1 more source

Factors that impact the accuracy with which nurses place preterm infants with respiratory distress syndrome in the prone position

open access: yesLa Pediatria Medica e Chirurgica, 2021
Prone positioning is an important treatment procedure for preterm infants with Respiratory Distress Syndrome (RDS). However, the accuracy with which preterm infants in the Neonatal Intensive Care Unit (NICU) are placed in the prone position is impacted ...
Nur Fitri, Defi Efendi
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

SIDS and infant sleeping position : audit on the advisory campaign in Malta [PDF]

open access: yes, 2008
Background: The baby’s sleeping position is the most important modifiable risk factor in Sudden Infant Death Syndrome (SIDS). The “back to sleep” position is safer than side or prone position.
Attard Montalto, Simon   +2 more
core  

Neurologic complications in percutaneous nephrolithotomy [PDF]

open access: yes, 2013
Percutaneous nephrolithotomy (PCNL) has been the preferred procedure for the removal of large renal stones in Iran since 1990. Recently, we encountered a series of devastating neurologic complications during PCNL, including paraplegia and hemiplegia ...
Abedinzadeh, Mehdi.   +18 more
core   +1 more source

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