Results 71 to 80 of about 4,150,880 (292)

Factors that impact the accuracy with which nurses place preterm infants with respiratory distress syndrome in the prone position

open access: yesLa Pediatria Medica e Chirurgica, 2021
Prone positioning is an important treatment procedure for preterm infants with Respiratory Distress Syndrome (RDS). However, the accuracy with which preterm infants in the Neonatal Intensive Care Unit (NICU) are placed in the prone position is impacted ...
Nur Fitri, Defi Efendi
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Lumbar Discectomy of a Patient of Mitral Stenosis with Chronic Atrial Fibrillation Under Epidural Anaesthesia

open access: yesIndian Journal of Anaesthesia, 2008
A 60-year-old female patient posted for discectomy of lumbar region L 3 -L 4 was accidently diagnosed to have chronic atrial fibrillation of rheumatic aetiology.This is a case report of this patient of critical mitral stenosis with mild mitral ...
Vinaya R Kulkarni   +3 more
doaj  

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Prone single-position extreme lateral interbody fusion (Pro-XLIF): preliminary results

open access: yesEuropean spine journal, 2020
Background Single-position options for combined anterior and posterior fusion in the lumbar spine have been suggested to reduce the surgical time and improve the efficiency of operating room.
C. Lamartina, P. Berjano
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Lateral Position versus Prone Position for Cervical Laminoplasty: A Retrospective Comparative Study

open access: yesTherapeutics and Clinical Risk Management, 2020
Lin Du, 1, 2 Yanzheng Gao, 1 Kun Gao, 1 Guang Yang, 1 Shanjun Gao 2 1Department of Spine Surgery, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou City, Henan Province, People’s Republic of China;
Du L, Gao Y, Gao K, Yang G, Gao S
doaj  

A randomized clinical trial to assess the effectiveness of prone position on cardiorespiratory outcomes among infants with respiratory distress

open access: yesMAMC Journal of Medical Sciences, 2016
Aims: The aim of this study was to assess for and compare the effect of prone and supine position on cardiorespiratory outcome among infants with respiratory distress (RD) and to screen any complications during positioning.
Prerna Sharma   +3 more
doaj   +1 more source

Single-position prone lateral approach: cadaveric feasibility study and early clinical experience.

open access: yesNeurosurgical Focus, 2020
OBJECTIVE Lateral lumbar interbody fusion (LLIF) is a useful minimally invasive technique for achieving anterior interbody fusion and preserving or restoring lumbar lordosis.
J. Godzik   +7 more
semanticscholar   +1 more source

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