Results 241 to 250 of about 1,488,747 (297)

An LSPR-Based Kinetic Framework for Polyelectrolyte Molecular Weight Determination: A Proof-of-Concept Study. [PDF]

Anal Chem
Mooney RM, Brainin C, Johal MS.
europepmc   +1 more source

Bifunctional Surfaces With Immobilized Antibodies and Bioactive Peptides Mediate Selective Capture and Proliferation of Endothelial Colony‐Forming Cells

Advanced Healthcare Materials, EarlyView.
A tunable bifunctional surface is developed by combining Fc‐binding peptides and RGD motifs to present oriented antibodies alongside integrin‐mediated signaling. The platform selectively captures endothelial colony‐forming cells while promoting their adhesion and proliferation.
Hugo A. Level, Marc‐Antoine Campeau, Mohamed A. Elkhodiry, Gaétan Laroche, Jean‐François Tanguay, Corinne A. Hoesli   +5 more
wiley   +1 more source

Bedtime regularization as a potential adjunct therapy for hypertension: a proof-of-concept study. [PDF]

Sleep Adv
Thosar SS, Sreeramadas AM, Jones M, Chaudhary N, Floyd-Driscoll C, McHill AW, Minson CT, Rope R, Emens JS, Shea SA, Brito LC.   +10 more
europepmc   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsaturated Lipids for Combined Antioxidant, Anti‐Apoptotic, and Neurotrophic Treatments

Advanced Healthcare Materials, EarlyView.
Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise, Fucen Luo, Borislav Angelov, Yuru Deng, Angelina Angelova   +4 more
wiley   +1 more source

Integrating more walking into public transit commuting: a proof-of-concept study. [PDF]

BMC Public Health
Hadas Y, Katz DE, Rabinowitz J.
europepmc   +1 more source

Proof-of-concept study of clinical use of blood-based MAVS biosensor in predicting immunotherapy response in SCLC patients. [PDF]

Transl Oncol
Amato L, Tavoletta I, De Rosa C, Seggio M, Arcadio F, Capaldo S, Ul Haq F, Tuccillo C, Esposito C, di Guida G, Iommelli F, De Rosa V, Reginelli A, Cappabianca S, Morgillo F, Ciardiello F, Nardone V, Cennamo N, Della Corte CM, Zeni L.   +19 more
europepmc   +1 more source

A proof-of-concept study: investigating the impact of COMT genotype and proline on negative symptoms in Alzheimer's disease. [PDF]

BJPsych Open
Clelland JD, Cure HW, Canizares AM, Anderson JH, Rawal B, Wong SA, Kerner N, Huey ED, Honig LS, Devanand DP, Clelland CL.   +10 more
europepmc   +1 more source

Dynamic Ultrasound of the Infrapatellar Fat Pad for Detecting Anterior Cruciate Ligament Deficiency: A Biomechanical Cadaveric Proof-of-Concept Study. [PDF]

Diagnostics (Basel)
Tokuda Y, Nakamura T, Shiraishi Y, Hori K, Okuda H, Ozaki N.   +5 more
europepmc   +1 more source