Results 251 to 260 of about 1,488,747 (297)

Prognostic value of cardiac fibroblast activation heterogeneity assessed by FAPI PET radiomics in hypertrophic cardiomyopathy: a proof-of-concept study. [PDF]

Open Heart
Song H, Ding J, Zhao J, Wang Y, Wu Q, Yang M, Wang L.   +6 more
europepmc   +1 more source

A Novel Compression Garment With a Dynamic External Lymphatic Drainage System: A Proof of Concept Study. [PDF]

Aesthet Surg J Open Forum
Mojallal A, Boucher F, Ei Messioui Z, Clément L, Oubari H.   +4 more
europepmc   +1 more source

The Effects of Orexin Receptor Antagonism During Early Withdrawal in Stimulant Use Disorder: Protocol for a Proof-of-Concept Study.

JMIR Res Protoc
Webber H, Tran N, Blake R, Goldman S, George T, Bailey B, Suchting R, Yoon J, Vincent J, Weaver M, Schmitz J, Lane S.   +11 more
europepmc   +1 more source

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A Proof-of-Concept Study of a Magnetorheological Micropump

Volume 2B: Advanced Manufacturing, 2022
Abstract In this paper, we studied a flap valve micro-fluidic pump that relies on an electromagnetic actuation mechanism. The upper wall pump chamber is made of a smart material called magnetorheological elastomer (MRE). Under a magnetic field, the upper wall contracts, and the amount of contraction depends on the intensity of the ...
Sevki Cesmeci, Rubayet Hassan, Mark Thompson   +2 more
openaire   +1 more source

Proof of Concept Study,

1981
Abstract : Field test data were analyzed and computer simulations performed to validate the predictions of an earlier study, which calculated the minimum detectable quantities (MDQ's) of trace gases that can be detected remotely using high-resolution spectroscopy.
M. Ahmadjian, F. P. DelGreco, A. S. Zachor   +2 more
openaire   +1 more source

Managing Expectations in the Transition to Proof of Concept Studies

Reviews on Recent Clinical Trials, 2017
As we move away from the traditional chemotherapy era to targeted therapy, the validity of old assessment paradigms associated with therapeutics are being raised in the context of immunotherapy. The old paradigm required elaborating on the toxicity assessment, with no expectation of efficacy in early phase trials. Safety data from Phase 1 and 2 studies
Thomas, Kieber-Emmons, Issam, Makhoul, Angela, Pennisi, Eric R, Siegel, Peter D, Emanuel, Bejotaloh, Monzavi-Karbassi, Zenon, Steplewski, J Thaddeus, Beck, Laura F, Hutchins   +8 more
openaire   +2 more sources

Analysis of a Proof of Concept Study

2017
From the data analysis perspective, clinical statisticians are typically faced with continuous data, discrete data, or time-to-event data. For early Phase II clinical trials, the most frequently seen data types are continuous data or binary data. In this chapter, and the next two chapters covering data analysis, the discussion will mainly be about ...
Naitee Ting, Ding-Geng Chen, Shuyen Ho, Joseph C. Cappelleri   +3 more
openaire   +1 more source