Results 21 to 30 of about 1,488,747 (297)

Not Just a Theory—The Utility of Mathematical Models in Evolutionary Biology [PDF]

open access: yes, 2014
Models have made numerous contributions to evolutionary biology, but misunderstandings persist regarding their purpose. By formally testing the logic of verbal hypotheses, proof-of-concept models clarify thinking, uncover hidden assumptions, and spur new
Brandvain, Y.   +7 more
core   +1 more source

Proton Grid Therapy: A Proof-of-Concept Study [PDF]

open access: yesTechnology in Cancer Research & Treatment, 2016
In this work, we studied the possibility of merging proton therapy with grid therapy. We hypothesized that patients with larger targets containing solid tumor growth could benefit from being treated with this method, proton grid therapy. We performed treatment planning for 2 patients with abdominal cancer with the suggested proton grid therapy ...
Henry, Thomas   +3 more
openaire   +2 more sources

Markerless vs. Marker-Based Gait Analysis: A Proof of Concept Study

open access: yesSensors, 2022
The analysis of human gait is an important tool in medicine and rehabilitation to evaluate the effects and the progression of neurological diseases resulting in neuromotor disorders.
Matteo Moro   +4 more
doaj   +1 more source

Flux-Based Formulation Development—A Proof of Concept Study [PDF]

open access: yesThe AAPS Journal, 2022
AbstractThe work aimed to develop the Absorption Driven Drug Formulation (ADDF) concept, which is a new approach in formulation development to ensure that the drug product meets the expected absorption rate. The concept is built on the solubility-permeability interplay and the rate of supersaturation as the driving force of absorption.
Kádár, Szabina   +11 more
openaire   +2 more sources

Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study [PDF]

open access: yes, 2014
The discovery of the tissue-protective activities of erythropoietin (EPO) has underlined the importance of some cytokines in tissue-protection, repair, and remodeling.
Annenkov, Alexander   +4 more
core   +3 more sources

Tele-pharmacy in rural Scotland: a proof of concept study [PDF]

open access: yesInternational Journal of Pharmacy Practice, 2017
Abstract Introduction Technology enables medical services to be provided to rural communities. This proof of concept study assessed the feasibility and acceptability of delivering community pharmacy services (CPS; including advice, sale of over-the-counter products and dispensing of prescriptions) by ...
Inch, Jackie   +10 more
openaire   +5 more sources

The Burden and Order of Proof in WTO Claims: Evolving Issues [PDF]

open access: yes, 2017
The World Trade Organization (WTO) is one of the best dispute settlement mechanisms in the world. Under WTO rules, aggrieved parties must establish a “prima facie” case before the panel can call on the offending party to respond to the claims.
Ahmad, Zeina, Malkawi, Bashar H.
core   +3 more sources

Cost-effectiveness and value of information analysis of a low-friction environment following skin graft in patients with burn injury

open access: yesPilot and Feasibility Studies, 2020
Background Patients with burn injuries may receive a skin graft to achieve healing in a timely manner. However, in around 7% of cases, the skin graft is lost (fails to attach to the wound site) and a re-grafting procedure is necessary.
Rebecca Kandiyali   +4 more
doaj   +1 more source

Functional Neuroimaging During Asleep DBS Surgery: A Proof of Concept Study

open access: yesFrontiers in Neurology, 2021
Object: A real-time functional magnetic resonance imaging (fMRI) feedback during ventral intermediate nucleus (VIM) deep brain stimulation (DBS) under general anesthesia (or “asleep” DBS) does not exist.
Francesco Sammartino   +5 more
doaj   +1 more source

A phase II multicentre, open-label, proof-of-concept study of tasquinimod in hepatocellular, ovarian, renal cell, and gastric cancers [PDF]

open access: yes, 2017
Background: Tasquinimod is a small molecule with immunomodulatory, anti-angiogenic, and anti-metastatic properties that targets the tumor microenvironment.
Bjarnason, Georg A   +14 more
core   +1 more source

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