Results 81 to 90 of about 1,488,747 (297)

RNAi-mediated gene silencing in tick synganglia: A proof of concept study

BMC Biotechnology, 2008
Background Progress in generating comprehensive EST libraries and genome sequencing is setting the stage for reverse genetic approaches to gene function studies in the blacklegged tick (Ixodes scapularis).
Troiano Emily, Kenny Bronwyn, Karim Shahid, Mather Thomas N   +3 more
doaj   +1 more source

Detecting Suicidal Ideation on Forums: Proof-of-Concept Study

Journal of Medical Internet Research, 2018
In 2016, 44,965 people in the United States died by suicide. It is common to see people with suicidal ideation seek help or leave suicide notes on social media before attempting suicide. Many prefer to express their feelings with longer passages on forums such as Reddit and blogs.
Ahmet Emre Aladağ, Serra Muderrisoglu, Naz Berfu Akbas, Oguzhan Zahmacioglu, Haluk O Bingol   +4 more
openaire   +3 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Digital screening for postnatal depression: mixed methods proof-of-concept study

BMC Pregnancy and Childbirth, 2022
Background Depression during the postnatal year is prevalent in mothers (17%) and fathers (9%), and suicide is the leading cause of maternal death in this period.
Emily Eisner, Shôn Lewis, Charlotte Stockton-Powdrell, Ria Agass, Pauline Whelan, Clare Tower   +5 more
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A Pilot Study Investigating the Feasibility and Acceptability of a Parent-Only Behavioral Weight-Loss Treatment for Children with Autism Spectrum Disorder. [PDF]

, 2019
Evidence-based weight-loss treatments for children with autism spectrum disorder (ASD) are lacking. Therefore, a parent-based weight-loss treatment for children with ASD (PBT-ASD) was developed.
Boutelle, Kerri N, Drahota, Amy, Matheson, Brittany E   +2 more
core   +1 more source

Treatment of osteonecrosis of the femoral head by core decompression and implantation of fully functional ex vivo-expanded bone marrow-derived mesenchymal stem cells: a proof-of-concept study

Stem Cells and Cloning: Advances and Applications, 2019
Rodrigo Mardones,1 Daniel Camacho,1,2 Francisco Monsalvo1 Nicolás Zulch,1 Claudio Jofre,3 José J Minguell3 1Department of Orthopedics, Clínica Las Condes, Santiago, Chile; 2Department of Orthopedics, Instituto Traumatológico ...
Mardones R, Camacho D, Monsalvo F, Zulch N, Jofre C, Minguell JJ   +5 more
doaj  

A model testing study of cervical cancer screening behavior using rogers’s protection motivation theory

Scientific Reports
Cervical cancer is a major global health issue, particularly in developing countries. Pap smear-based cervical cancer screening (CCS) is crucial for prevention.
Mohammad Mehdi Mohammadi, Zohreh Karimi, Motahareh Shirani, Sona Elyasi, Hadiseh Monadi Ziarat   +4 more
doaj   +1 more source

Online support system for students in higher education: Proof-of-concept study [PDF]

, 2016
Background: Providing support to the increasing numbers of students facing mental health difficulties in higher education (HE) can be difficult due to stigma or lack of resources.
Burgstahler S, Committee of Vice-Chancelors and Principals (CVC), Department for Business Innovation and Skills., Gallagher R, Gallagher R, Hunot V, Royal College of Psychiatrists., Royal College of Psychiatrists., Sheehan D, Universities UK   +9 more
core   +1 more source