Results 91 to 100 of about 1,240,536 (266)

Proof Planning for Maintainable Configuration Systems [PDF]

open access: yes, 1998
Configuration is a complex task generally involving varying measures of constraint satisfaction, optimization, and the management of soft constraints.
Pechoucek, M., Bundy, Alan, Lowe, H.
core  

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi   +6 more
wiley   +1 more source

An interactive assistant for the definition of proof certificates [PDF]

open access: yes, 2016
The Foundational Proof Certificate (FPC) approach to proof evidence offers a flexible framework for the formal definition of proof semantics, described through its relationship to focused proof systems.
Chihani, Zakaria, Blanco, Roberto
core  

Why are Proof Complexity Lower Bounds Hard [PDF]

open access: yes, 2020
We formalize and study the question of whether there are inherent difficulties to showing lower bounds on propositional proof complexity. We establish the following unconditional result: Propositional proof systems cannot efficiently show that truth ...
Pich, Jan
core  

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Proof-theoretic analysis of termination proofs

open access: yesAnnals of Pure and Applied Logic, 1995
\textit{E. A. Cichoń} [in: Proof theory, Int. Summer School and Conf., Leeds, UK, 1990, 173-193 (1992; Zbl 0793.03057)] raised the question whether there is a relation between the order type of a termination ordering \(\prec\) and the lengths of reduction sequences in a rewrite system reducing under \(\prec\). \textit{D. Hofbauer} [Theor. Comput.
openaire   +2 more sources

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

open access: yesInternational Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam   +2 more
wiley   +1 more source

Teaching Geometric Reasoning: Proof by Pictures? [PDF]

open access: yes, 2007
The purpose of this study was to investigate students' understanding of proof and proof writing using a new three-column method. The new three-column method consists of the traditional "statements" and "reasons" columns but also contains a "picture ...
Hawkins, Matthew Lee
core  

Adaptive Observer for Coupled Wave PDE and Infinite ODE With Sampled Data and Unknown Input: Application to Brain Hemodynamics Estimation

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir   +2 more
wiley   +1 more source

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