Results 101 to 110 of about 5,071,272 (326)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Data-driven multinomial random forest: a new random forest variant with strong consistency

Journal of Big Data
In this paper, we modify the proof methods of some previously weakly consistent variants of random forest into strongly consistent proof methods, and improve the data utilization of these variants in order to obtain better theoretical properties and ...
JunHao Chen, XueLi Wang, Fei Lei
doaj   +1 more source

GOST 34.11-2018 Analysis in The Context of Zero-Knowledge Proofs

Безопасность информационных технологий
Zero-knowledge proofs are being increasingly applied to a wide range of tasks in modern distributed information systems. Of particular interest are such areas of activity as digital asset management systems, anonymous electronic voting systems, and ...
Vladlen D. Afonin, Sergey V. Zapechnikov, Igor A. Prostov   +2 more
doaj   +1 more source

Towards Uniform Certification in QBF [PDF]

Logical Methods in Computer Science
We pioneer a new technique that allows us to prove a multitude of previously open simulations in QBF proof complexity. In particular, we show that extended QBF Frege p-simulates clausal proof systems such as IR-Calculus, IRM-Calculus, Long-Distance Q ...
Leroy Chew, Friedrich Slivovsky
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

CBCT in Dental Research: Is Complexity Necessary? An Exploratory Proof-of-Concept Study

Journal of Functional Biomaterials
This exploratory proof-of-concept study aimed to develop and preliminarily evaluate a 3D-printed holder designed for reuse in cone beam computed tomography (CBCT) in dental research, particularly for comparative studies requiring pre- and post ...
Selma Tekin, Karim Oumalou, Selim Tekin, Rui B. Ruben, Margarida Franco, Nuno Alves, Cláudia Barbosa, Sandra Gavinha, Maria Conceição Manso, Tiago Reis   +9 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Complexity of Positivstellensatz proofs for the knapsack [PDF]

Computational Complexity, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +4 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source