Results 211 to 220 of about 1,774,744 (290)

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Managing Emotional Intensity Difficulties in Older Adults With Personality Disorders: A Proof-of-Concept Study. [PDF]

J Clin Psychol
Ekiz E, van Alphen SPJ, Ouwens MA, Videler AC.   +3 more
europepmc   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

A Novel Ultrasonic Welding-Assisted Thermoplastic Root Canal Obturation Technique: An Ex Vivo Proof-of-Concept Study. [PDF]

Clin Exp Dent Res
Alshehri M, Antonis C, Alamri H, AlQahtani A, Altamimi M.   +4 more
europepmc   +1 more source

Proof of Concept Methodology

A detailed plan for the methodology as well as instructions for the practice partners including objectives and tools that will be used with students teachers and partners in both phases of the WP for improving the service design learning scenarios digital format of the Navigator and the ...
openaire   +1 more source

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

Physics-informed neural network for predicting in vacuo vocal fold eigenmodes: A proof of concept study. [PDF]

JASA Express Lett
Al Khasawneh MEM, Döllinger M, Zhang Z.
europepmc   +1 more source

An Edible H2O2 Biosensor for Gastrointestinal Metabolites and Peroxidase Enzyme Quantification

Advanced Healthcare Materials, EarlyView.
We present an edible biosensor for gastric fluid analysis that integrates a caffeic acid–horseradish peroxidase redox system into an edible electrolyte‐gated transistor. The device enables rapid, low‐volume detection of H2O2 and, with minimal modification, metabolites and enzyme activity in simulated gastrointestinal conditions.
Valerio Francesco Annese, Elena Feltri, Pietro Rossi, Valerio Galli, Cristiano Bortolotti, João Paulo Vita Damasceno, Ivan K. Ilic, Dario Natali, Alessandro Luzio, Adrica Kyndiah, Mario Caironi   +10 more
wiley   +1 more source

HealthProcessAI: a technical framework and proof-of-concept for LLM-enhanced healthcare process mining. [PDF]

Front Artif Intell
Illueca-Fernandez E, Chen K, Seoane F, Abtahi F.   +3 more
europepmc   +1 more source