Results 21 to 30 of about 1,488,747 (298)
Proton Grid Therapy: A Proof-of-Concept Study [PDF]
Technology in Cancer Research & Treatment, 2016 In this work, we studied the possibility of merging proton therapy with grid therapy. We hypothesized that patients with larger targets containing solid tumor growth could benefit from being treated with this method, proton grid therapy. We performed treatment planning for 2 patients with abdominal cancer with the suggested proton grid therapy ...
Henry, Thomas +3 more
openaire +2 more sources
Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study [PDF]
, 2014 The discovery of the tissue-protective activities of erythropoietin (EPO) has underlined the importance of some cytokines in tissue-protection, repair, and remodeling.
Annenkov, Alexander +4 more
core +3 more sources
Flux-Based Formulation Development—A Proof of Concept Study [PDF]
The AAPS Journal, 2022 AbstractThe work aimed to develop the Absorption Driven Drug Formulation (ADDF) concept, which is a new approach in formulation development to ensure that the drug product meets the expected absorption rate. The concept is built on the solubility-permeability interplay and the rate of supersaturation as the driving force of absorption.
Kádár, Szabina +11 more
openaire +2 more sources
The Burden and Order of Proof in WTO Claims: Evolving Issues [PDF]
, 2017 The World Trade Organization (WTO) is one of the best dispute settlement mechanisms in the world. Under WTO rules, aggrieved parties must establish a “prima facie” case before the panel can call on the offending party to respond to the claims.
Ahmad, Zeina, Malkawi, Bashar H.
core +3 more sources
Tele-pharmacy in rural Scotland: a proof of concept study [PDF]
International Journal of Pharmacy Practice, 2017 Abstract Introduction Technology enables medical services to be provided to rural communities. This proof of concept study assessed the feasibility and acceptability of delivering community pharmacy services (CPS; including advice, sale of over-the-counter products and dispensing of prescriptions) by ...
Inch, Jackie +10 more
openaire +5 more sources
Pilot and Feasibility Studies, 2020 Background Patients with burn injuries may receive a skin graft to achieve healing in a timely manner. However, in around 7% of cases, the skin graft is lost (fails to attach to the wound site) and a re-grafting procedure is necessary.
Rebecca Kandiyali +4 more
doaj +1 more source
Functional Neuroimaging During Asleep DBS Surgery: A Proof of Concept Study
Frontiers in Neurology, 2021 Object: A real-time functional magnetic resonance imaging (fMRI) feedback during ventral intermediate nucleus (VIM) deep brain stimulation (DBS) under general anesthesia (or “asleep” DBS) does not exist.
Francesco Sammartino +5 more
doaj +1 more source
A phase II multicentre, open-label, proof-of-concept study of tasquinimod in hepatocellular, ovarian, renal cell, and gastric cancers [PDF]
, 2017 Background: Tasquinimod is a small molecule with immunomodulatory, anti-angiogenic, and anti-metastatic properties that targets the tumor microenvironment.
Bjarnason, Georg A +14 more
core +1 more source
Mucosal adhesion and anti-inflammatory effects of Lactobacillus rhamnosus GG in the human colonic mucosa. A proof-of-concept study [PDF]
, 2018 AIM To investigate the adhesion and anti-inflammatory effects of Lactobacillus rhamnosus GG (LGG) in the colonic mucosa of healthy and ulcerative colitis (UC) patients, both in vivo and ex vivo in an organ culture model.
Corleto, Vito Domenico +6 more
core +1 more source
A small molecule inhibitor of HER3: a proof-of-concept study [PDF]
Biochemical Journal, 2020 Despite being catalytically defective, pseudokinases are typically essential players of cellular signalling, acting as allosteric regulators of their active counterparts. Deregulation of a growing number of pseudokinases has been linked to human diseases, making pseudokinases therapeutic targets of interest.
Audrey Colomba +16 more
openaire +4 more sources