Results 121 to 130 of about 167,450,079 (281)

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source

Is Ethereum Proof of Stake Sustainable? : Considering from the Perspective of Competition Among Smart Contract Platforms

, 2023
Ethereum はThe Merge アップデート以降、Proof of Stake に移行したことで消費電力がより小さく、また、より安全になったと喧伝されている。しかし、仮にそうだとして、その状態は持続できるのだろうか。この論文では、Ethereum のネイティブ通貨であるEther (ETH)の価格が他のスマートコントラクト基盤との競争の影響を受けうることに注目し、Proof of Stake の設計がもたらすとされる安全性と持続可能性について疑問を投げかける。Since the Merge ...
北村, 行伸, SOEJIMA, Yutaka, SAITO, Kenji, KITAMURA, Yukinobu, 副島, 豊, 杉浦, 俊彦, SUGIURA, Toshihiko, 斉藤, 賢爾, IWAMURA, Mitsuru, 岩村, 充   +9 more
core  

Highly Flexible and Conformable ZnO/FeGa Magnetoelectric Heterostructures for Skin wound Healing

Advanced Science, EarlyView.
The magnetic field‐induced electric field generated by a highly flexile ZnO(piezoelectric)/FeGa(magnetostrictive) magnetoelectric heterostructure embedded in the low Young's modulus elastomer PDMS has been used to stimulate the wound healing processes.
Filippos Perdikos, Laia Bagur, Cristina Vaca, Aritz Lafuente, Joaquin Llacer‐Wintle, Bojan Ambrožič, Christina Stefani, Minsoo Kim, Goran Dražić, Darja Lisjak, Jordi Sort, Xiang‐Zhong Chen, Maria Jose Esplandiu, Salvador Pané, Carme Nogués, Josep Nogués, Andreu Blanquer, Borja Sepúlveda   +17 more
wiley   +1 more source

GPoS: Geospatially-aware Proof of Stake

ACM Transactions on the Web
Geospatial decentralization is essential for blockchains, ensuring regulatory resilience, robustness, and fairness. We empirically analyze five major Proof of Stake (PoS) blockchains—Aptos, Avalanche, Ethereum, Solana, and Sui—revealing that a few geographic regions dominate consensus voting power, resulting in limited geospatial decentralization.
Shashank Motepalli, Naman Garg, Gengrui Zhang 0001, Hans-Arno Jacobsen   +3 more
openaire   +3 more sources

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Proof of stake-based blockchain applications

, 2019
This project aims to explore the benefit of Proof of Stake and implements demonstrative IoT ( Internet of Things ) applications using blockchain technology.
Fecho, Tyrone Jiale
core  

Dynamic Etching‐Induced Cl‐Terminated Ti3C2Clx/Ti3ZnC2 Heterostructure for Ammonia Electrosynthesis and Zinc‐Nitrogen Batteries

Advanced Science, EarlyView.
A stable Ti3C2Clx/Ti3ZnC2 heterostructure, fabricated by dynamic etching, exhibits outstanding electrocatalytic NRR activity (NH3 yield: 20.1 µg h−1 mg−1, FE: 38.1%) in alkaline media. The corresponding Zn‐N2 battery achieves a peak power density of 36.5 µW cm−2 and an NH3 yield of 13.1 µg h−1 mg−1, providing an advanced strategy for NH3 and ...
Yu Wang, Ying Sun, Liqun Ye, Jichi Liu, Hui Li, Yang Fu, Fengzhan Sun, Jieshan Qiu, Chang Yu, Tianyi Ma   +9 more
wiley   +1 more source

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

Advanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li, Jin Ning, An Wang, Minxi Shi, Yuanze Chen, Guoliang Liu, Shiquan Sun   +6 more
wiley   +1 more source

Ethereum 2.0 Hard Fork: Consensus Change and Market Efficiency

The Journal of The British Blockchain Association
This study investigates the impact of consensus mechanism changes on cryptocurrency markets within the framework of the efficient market hypothesis, focusing on Ethereum’s transition from Proof-of-Work to Proof-of-Stake consensus, known as the Ethereum 2.
Joongho Ahn, Professor Eojin Yi, Moonsoo Kim   +2 more
doaj   +1 more source