MK-0448, a Specific Kv1.5 Inhibitor: Safety, Pharmacokinetics and Pharmacodynamic Electrophysiology in Experimental Animal Models and in Humans. [PDF]
BACKGROUND: -We evaluated the viability of I(Kur) as a target for maintenance of sinus rhythm in patients with a history of atrial fibrillation through the testing of MK-0448, a novel I(Kur) inhibitor.
Bilodeau, Mark T +13 more
core +1 more source
Inhibition of L‐type calcium current by propafenone in single myocytes isolated from the rabbit atrioventricular node [PDF]
Jules C. Hancox, John S. Mitcheson
openalex +1 more source
Antiarrhythmic therapy effects on quality of life among patients with extrasystoles
To investigate antiarrhythmic therapy effectiveness, safety and impact on quality of life (QoL) among patients with symptomatic extrasystolia, a study was performed in 152 individuals, with 140 completing the study. Mean age of the patients was 57 years;
V. L. Doshchitsyn +6 more
doaj
Other than anticoagulation, what is the best therapy for those with atrial fibrillation? [PDF]
Rate control with long-term anticoagulation is recommended for most patients with atrial fibrillation (strength of recommendation [SOR]: A, based on randomized controlled trials [RCTs]).
Cadwallader, Kara +1 more
core
Propafenone versus procainamide for conversion of atrial fibrillation to sinus rhythm [PDF]
Anna Vittoria Mattioli +3 more
openalex +1 more source
Is there an isolated arrhythmogenic right atrial myocarditis? [PDF]
Two cases with drug refractory ectopic atrial tachycardia are described. A map-guided partial resection of the right atrium (RA) was done after preoperative endocardial catheter mapping hadshown well-defined areas of fractionated RA potentials ...
FROMER, M. +4 more
core
Review : Electrophysiologic and Antiarrhythmic Effects of Propafenone: Focus on Atrial Fibrillation [PDF]
Miguel Valderrábano, Bramah N. Singh
openalex +1 more source
Propafenone effect on inotropic myocardial function in patients with recurrent atral fibrillation
Aim. To study the effects of three-month propafenone antiarrhythmic therapy (daily dose 450 mg) on inotropic myocardial function in patients with recurrent atrial fibrillation (AF). Material and methods.
I. G. Fomina +2 more
doaj
A23-6 Radiofrequency ablation of atrial flutter in patients with atrial fibrillation treated with propafenone or amiodarone [PDF]
Mariusz Pytkowski +6 more
openalex +3 more sources
Comparison of the Effects of Liposomal Amphotericin B and Conventional Amphotericin B on Propafenone Metabolism and Hepatic Cytochrome P-450 in Rats [PDF]
G. Inselmann +2 more
openalex +1 more source

