Results 31 to 40 of about 460,569 (242)

Prediction Method of Maximum Propagation Angle in Parabolic Equation Model over Irregular Terrain

open access: yesInternational Journal of Antennas and Propagation
The parabolic equation (PE) model is effective for predicting signal propagation over irregular terrains. The shift map method of the PE model is highly accurate and widely used for terrain propagation predictions.
Rui Zhang   +4 more
doaj   +1 more source

Improvement of SAMI2 with Comprehensive Photochemistry at Mid-Latitudes and a Preliminary Comparison with Ionosonde Data

open access: yesAtmosphere
Photochemistry can significantly affect the ionospheric status. Adopting a comprehensive photochemical scheme with 60 reactions, primarily based on the recent systematic study of ion chemistry by Richards in 2011, we revised the open-source SAMI2 (Sami2 ...
Yanli Hu   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Estimating Ionospheric Phase Scintillation Indices in the Polar Region from 1 Hz GNSS Observations Using Machine Learning

open access: yesRemote Sensing
Ionospheric scintillation represents a disturbance phenomenon induced by irregular electron density variations, predominantly occurring in equatorial, auroral, and polar regions, thereby posing significant threats to Global Navigation Satellite Systems ...
Zhuojun Han   +8 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Winter thunderstorms in Kamchatka [PDF]

open access: yesE3S Web of Conferences, 2019
Winter thunderstorms in Kamchatka are rare meteorological phenomena. To investigate the nature of this phenomenon, time variations of quasistatic electric field and meteorological quantities at «Paratunka» observatory, IKIR FEB RAS (φ = 52:97° N; λ = 158:
Smirnov Sergey   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Experimental Analysis of Atmospheric Ducts and Navigation Radar Over-the-Horizon Detection

open access: yesRemote Sensing, 2022
Since the height of sea detection radar antenna and ship targets is relatively low, it is generally believed that its over-the-horizon detection is mainly caused by the evaporation duct at sea.
Li-Feng Huang   +7 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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