Results 21 to 30 of about 1,410 (120)

Antimalarial Potential of Synthetic Geraniol and Nerol Analogs

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Drug resistance is a major threat to malaria control; therefore, new drugs are required to combat this parasitosis. To accelerate drug development, the exploration of natural compounds or the repositioning of drugs already employed for other diseases is of particular interest.
Maurício Mazzine Filho, Isaac Agnelo Da Silva Sobreiro, Gabriel Dos Santos E. Silva, Carlos Alberto De Araújo Silva, Leonardo Vinícius Nogueira Lima, Arthur Vicentini Furtado, João Vitor Da Silveira, Marcus Vinícius Nora De Souza, Matheus Felipe Silva Santos, Gabriela Oliveira Castro, Manoel Aparecido Peres, Marcell Crispim, Alejandro Miguel Katzin, Mauricio Frota Saraiva, Ignasi Bofill Verdaguer, Munmun Bardhan   +15 more
wiley   +1 more source

Real‐Time Detection of Reduced Nitroreductase with a Reversible Fluorescent Probe

Advanced Science, Volume 12, Issue 42, November 13, 2025.
The first reversible binding probe (rNTRp) is presented that selectively detects the nitroreductase enzyme's active, reduced form (red‐NTR) with a fluorescence turn‐on response. Contrary to the conventional reaction‐based probes known to date, which provide only static information on the accumulated enzyme activity at a given time, rNTRp allows ...
Sourav Sarkar, Anushree Shil, Yong Woong Jun, Yun Jae Yang, Ranran Cheng, Wenli Wu, Xuechen Li, Qiongzheng Hu, Kyo Han Ahn   +8 more
wiley   +1 more source

Synthesis and Polymerization of Thiophene‐Bearing 2‐Oxazolines and 2‐Oxazines

Macromolecular Rapid Communications, Volume 46, Issue 6, March 2025.
Thiophene‐bearing 2Ox and 2Ozi monomers are produced by utilizing the Witte and Seeliger method. The monomers are characterized by spectroscopic methods and x‐ray diffraction to resolve structural data and properties. Homopolymers synthesized using thiophene‐substituted monomers produced thermally stable products and glass transition temperature can be
Aaron Lee, Julian Heck, Josef Goding, Robert Luxenhofer, Rylie A. Green   +4 more
wiley   +1 more source

Nickel‐Catalyzed O‐Arylation of N‐Protected Amino Alcohols with (Hetero)aryl Chlorides

Chemistry – A European Journal, Volume 31, Issue 10, February 17, 2025.
The first effective base metal‐catalyzed protocol for C−O cross‐coupling of primary, secondary, and tertiary alcohol‐containing N‐Boc protected amino alcohols with (hetero)aryl chlorides, affording access to new and useful N‐protected aryloxyamine compounds, is reported.
Kathleen M. Morrison, Emily C. Jackson, Erika M. H. Elliott, Mark Stradiotto   +3 more
wiley   +1 more source

Straightforward Synthesis of 1‐aryloxy‐1,1‐difluoro‐3‐aminopropan‐2‐ols – Accessing Fluorinated Derivatives of Commercialized Beta‐Blockers

European Journal of Organic Chemistry, Volume 27, Issue 35, September 16, 2024.
An array of 1‐aryloxy‐1,1‐difluoro‐3‐aminopropan‐2‐ols were synthesized using iodohydroxylation of gem‐difluorinated allyl aryl ethers followed by epoxidation and ring‐opening with an amine in a one‐pot/two‐step fashion. This approach allows the synthesis of a set of gem‐difluorinated derivatives of commercialized beta‐blockers.
Jan‐Ole Moritz, Shuang Liu, Katharina Konieczny, Dirk Michalik, Udo Kragl, Helfried Neumann, Matthias Beller   +6 more
wiley   +1 more source

Crystal structures, electron spin resonance, and thermogravimetric analysis of three mixed‐valence copper cyanide polymers

Acta Crystallographica Section C, Volume 80, Issue 6, Page 212-220, June 2024.
The crystal structures of three mixed‐valence copper cyanide polymers with similar polymeric CuCN networks are described, together with the results of electron spin resonance and thermogravimetric analyses.The crystal structures of three mixed‐valence copper cyanide alkanolamine polymers are presented, together with thermogravimetric analysis (TGA) and
Peter W. R. Corfield, Ahmed Elsayed, Tristan DaCunha, Christopher Bender   +3 more
wiley   +1 more source

Evaluation of fresh state, rheological properties, and compressive strength performance of cementitious system with grinding aids

Journal of Applied Polymer Science, Volume 141, Issue 15, April 15, 2024.
Synergic Interaction of Amine Based GAs with PCE cement systems. Abstract Grinding aids (GA) affect the fresh and hardened state properties of cement systems in addition to the economic and ecological advantages they provide. Nevertheless, there is not enough information in the literature regarding the effect of GA utilization on the rheological ...
Yahya Kaya, Veysel Kobya, Ali Mardani
wiley   +1 more source

Evaluation of efficacy and safety of esmolol in treating patients with septic shock: A protocol for systematic review and meta-analysis. [PDF]

Medicine (Baltimore), 2022
Hou B, Cai K, Li Y, Hu C, Pu X.
europepmc   +1 more source

Comparison of amiodarone and esmolol for prevention of reperfusion ventricular fibrillation in individuals undergoing heart valve or aortic surgery: a study protocol for a randomized controlled clinical trial. [PDF]

Trials, 2023
Zhu D, Li Y, Tian AY, Wang HN.
europepmc   +1 more source

Analysis of Complex Absorption After Multiple Dosing: Application to the Interaction Between the P-glycoprotein Substrate Talinolol and Rifampicin. [PDF]

Pharm Res, 2022
Weiss M, D'Argenio DZ, Siegmund W.
europepmc   +1 more source