Results 41 to 50 of about 1,585 (172)

Real‐Time Detection of Reduced Nitroreductase with a Reversible Fluorescent Probe

Advanced Science, Volume 12, Issue 42, November 13, 2025.
The first reversible binding probe (rNTRp) is presented that selectively detects the nitroreductase enzyme's active, reduced form (red‐NTR) with a fluorescence turn‐on response. Contrary to the conventional reaction‐based probes known to date, which provide only static information on the accumulated enzyme activity at a given time, rNTRp allows ...
Sourav Sarkar, Anushree Shil, Yong Woong Jun, Yun Jae Yang, Ranran Cheng, Wenli Wu, Xuechen Li, Qiongzheng Hu, Kyo Han Ahn   +8 more
wiley   +1 more source

Non-Systemic Drugs: A Critical Review [PDF]

, 2012
Non-systemic drugs act within the intestinal lumen without reaching the systemic circulation. The first generation included polymeric resins that sequester phosphate ions, potassium ions, or bile acids for the treatment of electrolyte imbalances or ...
Charmot, Dominique
core   +3 more sources

Synthesis and Polymerization of Thiophene‐Bearing 2‐Oxazolines and 2‐Oxazines

Macromolecular Rapid Communications, Volume 46, Issue 6, March 2025.
Thiophene‐bearing 2Ox and 2Ozi monomers are produced by utilizing the Witte and Seeliger method. The monomers are characterized by spectroscopic methods and x‐ray diffraction to resolve structural data and properties. Homopolymers synthesized using thiophene‐substituted monomers produced thermally stable products and glass transition temperature can be
Aaron Lee, Julian Heck, Josef Goding, Robert Luxenhofer, Rylie A. Green   +4 more
wiley   +1 more source

Synthesis and biological evaluation of thiazolidinedione derivatives of chalcones and flavones as antihyperglycemic and antidyslipidemic agents  [PDF]

, 2021
A series of chalcone and flavone derivatives (6a-d, 9a-f) based on 2,4-thiazolidinedione have been synthesized and evaluated for in vivo antihyperglycemic activity in sucrose loaded (SLM) and streptozotocin (STZ) induced diabetic animal models and also ...
Pratap, Ram , Satyanarayana, Mavurapu , Shukla, Poonam , Srivastava, Arvind K, Tiwari, Priti , Tripathi, Brajendra K   +5 more
core   +4 more sources

Characterization of a solvent for chemical absorption-based CO2 capture [PDF]

, 2021
The diploma thesis is focused on the thermodynamic characterization of an aqueous 3-amino-1-propanol (AP) solution, which is used as a promising solvent for post-combustion CO2 capture from exhaust gases.
Bunevska, Tanja
core  

Nickel‐Catalyzed O‐Arylation of N‐Protected Amino Alcohols with (Hetero)aryl Chlorides

Chemistry – A European Journal, Volume 31, Issue 10, February 17, 2025.
The first effective base metal‐catalyzed protocol for C−O cross‐coupling of primary, secondary, and tertiary alcohol‐containing N‐Boc protected amino alcohols with (hetero)aryl chlorides, affording access to new and useful N‐protected aryloxyamine compounds, is reported.
Kathleen M. Morrison, Emily C. Jackson, Erika M. H. Elliott, Mark Stradiotto   +3 more
wiley   +1 more source

Straightforward Synthesis of 1‐aryloxy‐1,1‐difluoro‐3‐aminopropan‐2‐ols – Accessing Fluorinated Derivatives of Commercialized Beta‐Blockers

European Journal of Organic Chemistry, Volume 27, Issue 35, September 16, 2024.
An array of 1‐aryloxy‐1,1‐difluoro‐3‐aminopropan‐2‐ols were synthesized using iodohydroxylation of gem‐difluorinated allyl aryl ethers followed by epoxidation and ring‐opening with an amine in a one‐pot/two‐step fashion. This approach allows the synthesis of a set of gem‐difluorinated derivatives of commercialized beta‐blockers.
Jan‐Ole Moritz, Shuang Liu, Katharina Konieczny, Dirk Michalik, Udo Kragl, Helfried Neumann, Matthias Beller   +6 more
wiley   +1 more source

Effects of congeners of amphetamine on the human heart [PDF]

Central stimulatory and hallucinogenic drugs of abuse like amphetamine and most congeners of amphetamine can have cardiac harmful effects. These cardiac side effects can lead to morbidities and death.
Dhein, Stefan, Gergs, Ulrich, Hofmann, Britt, Kirchhefer, Uwe, Neumann, Joachim   +4 more
core   +1 more source

Crystal structures, electron spin resonance, and thermogravimetric analysis of three mixed‐valence copper cyanide polymers

Acta Crystallographica Section C, Volume 80, Issue 6, Page 212-220, June 2024.
The crystal structures of three mixed‐valence copper cyanide polymers with similar polymeric CuCN networks are described, together with the results of electron spin resonance and thermogravimetric analyses.The crystal structures of three mixed‐valence copper cyanide alkanolamine polymers are presented, together with thermogravimetric analysis (TGA) and
Peter W. R. Corfield, Ahmed Elsayed, Tristan DaCunha, Christopher Bender   +3 more
wiley   +1 more source

Evaluation of fresh state, rheological properties, and compressive strength performance of cementitious system with grinding aids

Journal of Applied Polymer Science, Volume 141, Issue 15, April 15, 2024.
Synergic Interaction of Amine Based GAs with PCE cement systems. Abstract Grinding aids (GA) affect the fresh and hardened state properties of cement systems in addition to the economic and ecological advantages they provide. Nevertheless, there is not enough information in the literature regarding the effect of GA utilization on the rheological ...
Yahya Kaya, Veysel Kobya, Ali Mardani
wiley   +1 more source