Results 61 to 70 of about 486,560 (293)
Adaptive Experimental Design Using the Propensity Score [PDF]
Many social experiments are run in multiple waves, or are replications of earlier social experiments. In principle, the sampling design can be modified in later stages or replications to allow for more efficient estimation of causal effects.
Hahn, Jinyong +2 more
core +4 more sources
Treatment of Solitary Painful Osseous Metastases with Radiotherapy, Cryoablation or Combined Therapy: Propensity Matching Analysis in 175 Patients [PDF]
, 2015 aim of this study was to identify outcomes in pain relief and quality of life in patients with a solitary painful osseous metastasis treated by radiotherapy, cryoablation or the combination using a propensity score matching study ...
Bonfili, Pierluigi +11 more
core +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Propensity Score Method for Partially Matched Omics Studies
Cancer Informatics, 2014 This paper focuses on the problem of partially matched samples in the presence of confounders. We propose using propensity score matching to adjust for confounding factors for the subset of data with incomplete pairs, followed by integrating the P ...
Pei-Fen Kuan
doaj +1 more source
Causal Effects in Non-Experimental Studies: Re-Evaluating the Evaluation of Training Programs [PDF]
This paper uses propensity score methods to address the question: how well can an observational study estimate the treatment impact of a program? Using data from Lalonde's (1986) influential evaluation of non-experimental methods, we demonstrate that ...
Rajeev H. Dehejia, Sadek Wahba
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Selection of Control Variables in Propensity Score Matching: Evidence from a Simulation Study [PDF]
Propensity score matching is a widely-used method to measure the effect of a treatment in social as well as health sciences. An important issue in propensity score matching is how to select conditioning variables in estimation of the propensity score. It
Nguyen Viet, Cuong
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Application of the Generalized Propensity Score. Evaluation of public contributions to Piedmont enterprises. [PDF]
In this article, we apply a generalization of the propensity score of Rosenbaum and Rubin (1983b). Techniques based on the propensity score have long been used for causal inference in observational studies for reducing bias caused by non-random treatment
Bia, Michela, Mattei, Alessandra
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source