Results 81 to 90 of about 3,851,696 (287)
BMC Infectious DiseasesBackground The diagnostic process is a key element of medicine but it is complex and prone to errors. Infectious diseases are one of the three categories of diseases in which diagnostic errors can be most harmful to patients.
Anna M. Eikenboom +3 more
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Propensity Score Method for Partially Matched Omics Studies
Cancer Informatics, 2014 This paper focuses on the problem of partially matched samples in the presence of confounders. We propose using propensity score matching to adjust for confounding factors for the subset of data with incomplete pairs, followed by integrating the P ...
Pei-Fen Kuan
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Neutrophil-to-lymphocyte ratio is a prognostic factor for colon cancer: a propensity score analysis
BMC Cancer, 2020 A large number of patients suffer recurrence after curative resection, and mortality from colon cancer remains high. The role of systemic inflammatory response, as reflected by neutrophil-to-lymphocyte ratio (NLR), in cancer recurrence and death has been
J. Mazaki +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Covariate adjusted nonparametric methods under propensity analysis
Frontiers in Applied Mathematics and StatisticsPropensity score is one of the most commonly used score functions in adjusting for covariates effect in statistical inference. It is important to understand the impact with propensity score in case some of the prespecified covariates are severely ...
Jiabu Ye, Dejian Lai
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Journal of Clinical Oncology, 2019 PURPOSE Gastric cancer (GC) with peritoneal metastases (PMs) is a poor prognostic evolution. Cytoreductive surgery (CRS) yields promising results, but the impact of hyperthermic intraperitoneal chemotherapy (HIPEC) remains controversial. Here we aimed to
P. Bonnot +24 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Generalized Propensity Score Matching with Multilevel Treatment Options
Journal of Health Economics and Outcomes Research, 2013 # Background Although conventional form of propensity score matching (PSM) is widely used in outcomes research field, its application on multilevel treatment is limited. # Objectives This article reviews PSM and illustrates their use when there are more
Onur Baser
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Evaluation of the Causal Association of Risk Factors for Death From COVID-19 Patients Admitted to Golestan Hospitals by Propensity Score Estimation Method [PDF]
علوم بهداشتی ایران, 2023 Background and Purpose: Evaluating the causal association effect of risk factors is essential in estimating the mortality rate among COVID-19 patients.
Hassan Khorsha +2 more
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