Results 131 to 140 of about 2,349,452 (293)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Extensions of the Dynamic Propensity Score Adjustment for Longitudinal Data [PDF]

, 2017
Dynamic propensity adjustment models are extensions of the propensity score adjustment strategy to longitudinal observational study data, in which observations on the same subjects are gathered repeatedly over time.
Colin Hubbard (7980833)
core   +1 more source

How Robust is the Evidence on the Returns to College Choice? Results Using Swedish Administrative Data [PDF]

We estimate the causal effect on earnings of graduating from old universities rather than new universities/university colleges. The study is based on Swedish administrative data that is comparatively rich in terms of school grades, parental ...
Eliasson, Kent
core  

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

The Adoption of Water Conservation and Intensification Technologies and Farm Income: A Propensity Score Analysis for Rice Farmers in Northern Ghana [PDF]

This study uses cross-sectional data of 342 small-scale lowland rice farmers in Northern Region of Ghana to analyze the impact of the adoption decision of bund construction and seed dibbling on net returns, input demand and output supply.
Faltermeier, Liane, Abdulai, Awudu
core  

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

High-dimensional mediation analysis for continuous outcome with confounders using overlap weighting method in observational epigenetic study

BMC Medical Research Methodology
Background Mediation analysis is a powerful tool to identify factors mediating the causal pathway of exposure to health outcomes. Mediation analysis has been extended to study a large number of potential mediators in high-dimensional data settings.
Weiwei Hu, Shiyu Chen, Jiaxin Cai, Yuhui Yang, Hong Yan, Fangyao Chen   +5 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Maternal smoking during pregnancy and birthweight - A propensity score matching approach [PDF]

There is accumulated evidence of the existence of a deleterious effect of smoking on birth outcomes. Understanding the effect of smoking on pregnancy is a critical issue because of the public policy implications for dissuading maternal smoking.
Ronald P. Wilder, Paula Veiga
core  

Propensity Score Adjustment in Measurement Invariance [PDF]

, 2017
Measurement invariance testing is prerequisite if meaningful comparisons of latent construct across groups are important to the study in social science.
Cao, Qian
core