Results 61 to 70 of about 206,310 (335)

Comparison between FOLFIRINOX and gemcitabine plus nab-paclitaxel including sequential treatment for metastatic pancreatic cancer: a propensity score matching approach [PDF]

, 2021
Jung Won Chun, Sang Hyub Lee, Joo Seong Kim, Namyoung Park, Gunn Huh, In Rae Cho, Woo Hyun Paik, Ji Kon Ryu, Yong‐Tae Kim   +8 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The feasibility of matching on a propensity score for acupuncture in a prospective cohort study of patients with chronic pain

BMC Medical Research Methodology, 2017
Background Propensity scores are typically applied in retrospective cohort studies. We describe the feasibility of matching on a propensity score derived from a retrospective cohort and subsequently applied in a prospective cohort study of patients with ...
Eric S. Johnson, John F. Dickerson, William M. Vollmer, Alee M. Rowley, Cheryl Ritenbaugh, Richard A. Deyo, Lynn DeBar   +6 more
doaj   +1 more source

Impact of informal institutions on youth agribusiness participation in Southern Benin

Agricultural and Food Economics, 2023
The agribusiness sector development is often portrayed as an essential component of economic development. Though Benin is a country with inestimable agricultural potential, the agribusiness sector appears unappealing to the local youths.
Kadoukpè Gildas Magbondé, Djana Mignouna, Victor Manyong, Razack Adéoti, Ayélé Odile Sossou   +4 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Aging Leads to Poor Outcome after Subarachnoid Hemorrhage through Exacerbating Early Brain Injury

Neurologia Medico-Chirurgica
Early brain injury after a subarachnoid hemorrhage is an important prognostic factor. Aging is also an important prognostic factor of subarachnoid hemorrhage. However, the association between early brain injury and aging remains unclear.
Tomofumi TAKENAKA, Masatoshi TAKAGAKI, Hajime NAKAMURA, Takeo NISHIDA, Masaaki TANIGUCHI, Akihiro TATEISHI, Maki KOBAYASHI, Shogo FUKUYA, Tomoaki MURAKAMI, Takeshi SHIMIZU, Takamune ACHIHA, Yuichi MATSUI, Shuhei YAMADA, Tatsumaru FUKUDA, Ryota NAKAGAWA, Takaki MATSUMURA, Hidekazu NAKATA, Yuhei HOSHIKUMA, Shingo TOYOTA, Akatsuki WAKAYAMA, Haruhiko KISHIMA   +20 more
doaj   +1 more source

Acquired agitation in acute respiratory distress syndrome with COVID-19 compared to influenza patients: a propensity score matching observational study [PDF]

, 2022
Adel Maamar, Clémence Liard, Willelm Doucet, Florian Reizine, Benoît Painvin, Flora Delamaire, Valentin Coirier, Quentin Quelven, Pauline Guillot, Mathieu Lesouhaitier, Jean‐Marc Tadié, Arnaud Gacouin   +11 more
openalex   +1 more source

Double-adjustment in propensity score matching analysis: choosing a threshold for considering residual imbalance

BMC Medical Research Methodology, 2017
BackgroundDouble-adjustment can be used to remove confounding if imbalance exists after propensity score (PS) matching. However, it is not always possible to include all covariates in adjustment.
Tri-Long Nguyen, G. Collins, J. Spence, J. Daurès, P. J. Devereaux, P. Landais, Y. Manach   +6 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source