Results 141 to 150 of about 5,794,188 (337)

Closedness of the Tangent Spaces to the Orbits of Proper Actions

open access: yesJournal of Lie Theory, 2008
In this note we show that for any proper action of a Banach--Lie group $G$ on a Banach manifold $M$, the corresponding tangent maps $\g \to T_x(M)$ have closed range for each $x \in M$, i.e., the tangent spaces of the orbits are closed. As a consequence, for each free proper action on a Hilbert manifold, the quotient $M/G$ carries a natural manifold ...
Jotz, Madeleine, Neeb, Karl-Hermann
openaire   +3 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Action Plans and Socio-Economic Evolutionary Change [PDF]

open access: yes
An important challenge to evolutionary economics consists of how to tackle with the dramatic tension between purposeful human action and the ‘blindness’ of evolutionary processes.
Muñoz, Félix, Encinar, María Isabel
core  

Logistic regression analysis of variables associated with proper action implementation of MPDSR in health facilities, Tigray, Northern Ethiopia, 2018 (N = 66).

open access: yes, 2019
Logistic regression analysis of variables associated with proper action implementation of MPDSR in health facilities, Tigray, Northern Ethiopia, 2018 (N = 66).
Degnesh Negash (7490762)   +8 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Orbifold-like and proper $\mathfrak g$-manifolds

open access: yes, 2022
In [4] and [5], we generalized the concept of completion of an infinitesimal group action $\zeta : {\mathfrak g} \to \mathfrak X (M)$ to an actual group action on a (non-compact) manifold $M$, originally introduced by R.
Michor, Peter W., Kamber, Franz W.
core  

Communicative Action's Democratic Deficit: A Critique of Habermas’s Contribution to Democratic Theory

open access: yesInternational Journal of Communication, 2009
In this paper, I develop a critique of Habermas’ concept of communicative action. My critique is based on the concept’s inability to grasp the complexities of democratic politics and democratic political action. I first show that the central seed of this
Martín Plot
doaj  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

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