Results 101 to 110 of about 2,187,591 (335)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

On the nature of proper names and definite descriptions from a cognitive perspective

open access: yesBucharest Working Papers in Linguistics, 2007
In the present study, I present an analysis of proper names and definite descriptions based on Machery et al. (2004), in the treatment of Petho (2005a), which I revisit by pointing at several theoretical aspects not detailed or not mentioned by Petho ...
Agota Osz
doaj  

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Amyotrophic Lateral Sclerosis Prevalence Projection in 2040: A Less Rare Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To project ALS prevalence across multiple countries through 2040, accounting for both population aging and increased survival. Methods Data from the Piemonte and Valle d'Aosta ALS register (PARALS) was used to estimate the trends in incidence and prevalence from 2005 to 2019. Survival trends over this period were also assessed.
Rosario Vasta   +18 more
wiley   +1 more source

Transformation of Ukrainian Name-giving Process: Historical Analysis

open access: yesCхід, 2019
The issue is devoted to a value sphere of Christian dominant consideration in the spiritual and semantic space of a name-giving culture in Ukrainian anthroponymic tradition as well as to the historical and philosophical analysis of spiritual ...
Irina Lomachinska   +2 more
doaj   +1 more source

Fusiform Gyrus Phospho-Tau is Associated with Failure of Proper Name Retrieval in Aging. [PDF]

open access: yesAnn Neurol, 2021
Tennant VR   +5 more
europepmc   +1 more source

THE TRANSLATION ANALYSIS OF PROPER NAMES IN FANTASY FILM “THE HOBBIT: AN UNEXPECTED JOURNEY” :A Case Study of English – Indonesian Translation: [PDF]

open access: yes, 2014
The present research entitled The Translation Analysis of Proper Names in Fantasy Film “The Hobbit: An Unexpected Journey” aims at discovering types of proper names and analyzing the translation procedures dealing with the proper names in the film.
Yulianto, Dimas
core  

Enhancing retinal images by nonlinear registration

open access: yes, 2014
Being able to image the human retina in high resolution opens a new era in many important fields, such as pharmacological research for retinal diseases, researches in human cognition, nervous system, metabolism and blood stream, to name a few.
Chenegros, Guillaume   +3 more
core   +3 more sources

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih   +40 more
wiley   +1 more source

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