Results 101 to 110 of about 13,775 (248)

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Introduction: Proper Names and Modes of Existence

open access: yesStudia Semiotyczne, 2022
DOI: https://doi.org/10.26333/sts.xxxvi1.01 This special issue of Semiotic Studies is devoted to proper names, and continues to some extent the line of research discussed in the contributions to the special issue of Organon F, 28(1), on names and ...
Piotr Stalmaszczyk
doaj  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Quasi-proper names, language use and contextualism [PDF]

open access: yes
In this paper, I discuss expressions such as ‘Dad’, ‘Mum’, ‘Grandpa’, etc., which are called ‘quasi-proper names’. These expressions can be used both to refer to a thing or person in an assertion in which a predicate is assigned to the referent expressed
Capone, Alessandro
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

The grammar of Orungu proper names [PDF]

open access: yes, 2011
International audienceAspects of the grammar of proper names in the Gabonese Bantu language Orungu are described and explained, with special attention for agreement and definiteness marking.
Ambouroue, Odette, van de Velde, Mark
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

LEARNING PROPER NAMES [PDF]

open access: yes
This article examines the position of proper names in the language and their difference from common names since ancient times.
Koziyeva Iqbol Komiljonovna
core  

Proper Names’ Classification in Modern German [PDF]

open access: yes, 2014
The article envisages the classifications of proper names (PN) made by the researchers A. Bakh, G. Bauer and V. Kamenets, their advantages and disadvantages are described, as well as our own onyms’ division is offered in accordance with the research ...
Белоус, И. Л.
core  

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