KRstereo: Predicting β-Hydroxy Stereochemistry in Polyketides Using Protein Language Models. [PDF]
J Chem Inf ModelTsai HY, Xu W, Xie WJ, Ding Y.
europepmc +1 more source
Advanced Intelligent Systems, EarlyView.Motion artifacts in electrocardiographic signals, conventionally dismissed as noise, are shown to encode discriminative activity information. A smart t‐shirt fusing textile strain sensors with textile ECG electrodes, processed through a complex‐valued residual network, recognizes 12 sport activities.
Nada Al‐azzawi +4 more
wiley +1 more source
Standards for Computational Methods in Drug Design and Discovery: Simplified Guidance for Authors and Reviewers. [PDF]
Drug Des Devel TherIbrahim TM, Hussain M, Boeckler FM.
europepmc +1 more source
MetaPaCS: A Novel Meta‐Learning Framework for Pancreatic Cancer Subtype Identification
Advanced Intelligent Systems, EarlyView.We have developed MetaPaCS, an ensemble meta‐learning framework for reliable prediction of pancreatic cancer subtypes with high accuracy. MetaPaCS is capable of capturing subtype‐specific distinct gene expression patterns and drug‐disease associations for pancreatic cancer.
Nick B. Peterson +4 more
wiley +1 more source
The Multiple Criteria Qualitative Value-Based Pricing Framework "MARIE" for Novel Cell and Gene Therapy. [PDF]
Clin Pharmacol TherTakami A, Igarashi A.
europepmc +1 more source
A Hierarchical, Model‐Based System for High‐Performance Humanoid Soccer
Advanced Intelligent Systems, EarlyView.A hierarchical model‐based humanoid soccer system built on ARTEMIS integrates compliant mechanism design, in‐gait kicking, perception, localization, collision‐aware navigation, and behavior planning. Hardware–software codesign aligns mechanical design and control strategy with the requirements of autonomous soccer.
Quanyou Wang +18 more
wiley +1 more source
Impact of automated scoring on interpreting performance and self-regulated learning: evidence from a pedagogical experiment. [PDF]
Front PsycholChen C, Liu T.
europepmc +1 more source
AI‐Based Mitochondrial Network Characterization as a Biomarker for DNM1L‐Related Disease Diagnosis
Advanced Intelligent Systems, EarlyView.This work provides proof‐of‐concept that AI‐based analysis of mitochondrial network morphology in patient‐derived fibroblasts can identify a phenotypic signature associated with DNM1L deficiency. This automated approach may ultimately provide a complementary functional readout for the interpretation of novel DNM1L variants following genetic testing ...
Uliana Musokhranova +9 more
wiley +1 more source
From MRI activity to treatment escalation in relapsing multiple sclerosis: what can new T2 lesions tell us? [PDF]
Front NeurolBuchka S, Mansmann U, Havla J.
europepmc +1 more source
An Active Knee–Ankle–Foot Orthosis With Torque‐Dense, Low‐Impedance Knee Actuation
Advanced Intelligent Systems, EarlyView.This article presents the simulation, design, and clinical validation of a robotic active KAFO with torque‐sensitive actuation. By passively and continuously adapting the transmission ratio in response to the knee torque, the torque‐sensitive actuator overcomes the tradeoff between torque, weight, and impedance observed in conventional robot actuators,
Brendon Ortolano +4 more
wiley +1 more source