Results 121 to 130 of about 25,639,299 (373)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Smart systems related to polypeptide sequences

AIMS Materials Science, 2016
Increasing interest for the application of polypeptide-based smart systems in the biomedical field has developed due to the advantages given by the peptidic sequence.
Lourdes Franco, Luís J. del Valle, Jordi Puiggalí   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Triggering of Land Subsidence in and Surrounding the Hangjiahu Plain Based on Interferometric Synthetic Aperture Radar Monitoring

Remote Sensing
In the early stages, uncontrolled groundwater extraction led to the Hangjiahu (HJH) Plain becoming one of the areas with the most severe land subsidence in China.
Zixin He, Zimeng Yang, Xiaoyong Wu, Tingting Zhang, Mengning Song, Ming Liu   +5 more
doaj   +1 more source

Integral Solution of the Interface Profile of Grain Boundary Grooving by Surface Diffusion

Advances in Materials Science and Engineering, 2012
In polycrystalline thin films, formation of grain boundary grooving is investigated widely due to its effects on their properties. Infinite series solution of the interface of grain-boundary grooving by surface diffusion has been obtained. In this paper,
Caifang Wang, Hui Xing, Fengping Yao, Changle Chen, Jianyuan Wang, Fei Fan   +5 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Spreadsheet Calculations Of Thermodynamic Properties [PDF]

, 2020
Tom R. Mincer, David McDaniel, L. S. Caretto   +2 more
openalex   +1 more source

Geometric properties of jet schemes [PDF]

, 2010
This paper shows how properties of jet schemes relate to those of the singularity on the base scheme. We will see that the jet scheme's properties of being Q-factorial, Q-Gorenstein, canonical, terminal and so on are inherited by the base scheme.Comment:
Ishii, Shihoko
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Magnetocaloric properties of nanocrystalline La0.125Ca0.875MnO3 [PDF]

, 2009
Anis Biswas, Tapas Samanta, S. Banerjee, I. Das   +3 more
openalex   +1 more source