Results 111 to 120 of about 8,906,865 (345)

On Residual Properties [PDF]

open access: yesProceedings of the American Mathematical Society, 1980
It is shown that the class of structures residually in a universal class closed under elementary equivalence is definable by a sentence of L ∞ ω {L_{\infty \omega }} .
openaire   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Qualitative factors of patents affecting technology commercialization in 2020: An analysis of U.S. registered patents

open access: yesJournal of Intellectual Property
The efficiency of government-funded R&D support in South Korea appears to be in need of improvement. The amount of patent transfers and total technology royalty income has decreased drastically.
Jaeheon Lee   +2 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

PTNS: patent citation trajectory prediction based on temporal network snapshots

open access: yesScientific Reports
With the rapid development of science and technology, the pace of development in the knowledge economy is accelerating. Intellectual property, especially patents, is a strategic resource for technological innovation and a crucial support for building an ...
Mingli Ding   +3 more
doaj   +1 more source

Does Intellectual Property Lead to Intellectual Property Protection? [PDF]

open access: yes
Researchers studying the differential commitment of countries to intellectual property rights, often appear to run into the claim that countries with a relatively higher and significantly changing technological base (the developed countries) opt for ...
Sunil Kanwar
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

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