Results 91 to 100 of about 6,751,316 (288)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Temporary consolidation and excavation of artifacts at waterlogged archaeological sites
Scientific ReportsEnsuring the preservation of fragile artifacts from waterlogged archaeological sites demands the advancement of extraction techniques that uphold both safety and the integrity of historical data.
Xue-Qiang Chen +4 more
doaj +1 more source
PHILOSOPHY OF WAR AND TRANSFORMATION OF CULTURAL VALUES IN CONDITIONS OF ARMED CONFLICT
Освітній дискурсRelevance of the research. The phenomenon of war is one of the most profound and tragic themes in the philosophical reflection on human existence.
Svitlana Solianyk, Olena Nevmerzhytska
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Освітній дискурсRelevance of the research topic. The study of intrapersonal communication, in particular the conflict between the alter ego and the super ego of the subject, is extremely relevant in the context of modern socio-political and psychosocial conditions that ...
Olga Kyvliuk, Oleksandr Khlon
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The Compact Approximation Property does not imply the Approximation Property
, 1992 It is shown how to construct, given a Banach space which does not have the approximation property, another Banach space which does not have the approximation property but which does have the compact approximation ...
Willis, George A.
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploring the Factors Influencing Project Management Methodology Implementation in Local Governments
Administrative SciencesThis study seeks to identify the factors influencing the implementation of Project Management Methodologies (PMM) in Local Government (LG) and identify the concepts, themes and characteristics that make up each of those factors.
Raj Ranasinghe +3 more
doaj +1 more source