Results 111 to 120 of about 1,515,460 (262)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Property Attribute and Property Ownership of Virtual Property

open access: yesProceedings of Business and Economic Studies
Virtual property has increasingly become a key issue, particularly regarding its nature, ownership, and goodwill acquisition, all of which are worthy of study. Analyzing these issues can contribute to a better understanding of how to develop laws and regulations to protect virtual property.
openaire   +1 more source

Outsourced property management : the regulations of the property manager

open access: yes, 2018
Purpose The purpose of this paper is to identify factors on property management level for analysing incentives for an effective property management in an outsourced setting. Design/methodology/approach This research is based on an interview study of
Peter Palm, Palm, Peter, Palm, Peter,
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Property research priorities in Australia

open access: yes, 2002
Using a survey conducted in 2001, property research priorities amongst Australian institutional property investors are examined. Forty property research topics are prioritised and then compared with equivalent USA property research priorities.
Worzala, Elaine M.   +2 more
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Exploring the Factors Influencing Project Management Methodology Implementation in Local Governments

open access: yesAdministrative Sciences
This study seeks to identify the factors influencing the implementation of Project Management Methodologies (PMM) in Local Government (LG) and identify the concepts, themes and characteristics that make up each of those factors.
Raj Ranasinghe   +3 more
doaj   +1 more source

UK Design as a Global Industry : International Trade and Intellectual Property [PDF]

open access: yes, 2012
The importance of design to the UK economy is widely recognised. It is one of the key pillars of the knowledge economy, it plays an important role in the innovation process, and it is one of a number of specialisms that help to set the UK apart from ...
Sissons, Andrew   +2 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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