Results 71 to 80 of about 2,926,022 (304)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The dynamics of New Zealand commercial property portfolios

open access: yes, 2005
The dynamics of commercial property portfolio peljormance in New Zealand have changed considerably in recent years, with most of these dynamics working in favour of commercial property in an investment portfolio.
Newell, Graeme
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Property Council of Australia federal pre-budget submission 2016-17

open access: yes, 2016
Property touches the lives of all Australians. It creates prosperity, jobs and strong communities. Property is both a major part of the household balance sheet and the Australian economy.
Property Council of Australia
core  

Synthesis of Network Graph-analytic Reports of Guard and Support of Dynamic Search Processes and Systems

open access: yesБезопасность информационных технологий, 2015
Methods and models of graph-analytic synthesis of network reports of protection and support of essentially nonlinear dynamic search processes and systems are considered.
Sergey Pavlovich Botuz   +1 more
doaj  

Lessons learnt from the use of relationship-based procurement methods in Australia: clients’ perspectives

open access: yesConstruction Economics and Building, 2016
This paper aims to review the use of various construction procurement systems and present the development of Relationship-Based Procurement (RBP) Methods currently in use within the Australian construction industry.
Farshid Rahmani   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Property as Intangible Property

open access: yes, 2020
Abstract Historically, property theory has focused on real property as the premier example of property, reflecting the longstanding importance of land as a source of wealth and political power. This essay argues that it is time for property theorists to pay more attention to intangible property. It makes three main points.
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Primacy of Property; Or, The Subordination of Property Rights

open access: yesSSRN Electronic Journal, 2021
AbstractA property right, the standard view maintains, is a proper subset of the most complete and comprehensive set of incidents for full ownership of a thing. The subsidiary assumption is that the pieces that are property rights compose the whole that is ownership or property, i.e., that property rights explain property.
openaire   +2 more sources

Home - About - Disclaimer - Privacy