Results 71 to 80 of about 1,355,305 (266)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
This study examines housing affordability among low income (B40) households in Greater Kuala Lumpur using a residual income framework that reflects essential household needs and cost-of-living realities.
Nor Suzylah Sohaimi +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
PHILOSOPHY OF WAR AND TRANSFORMATION OF CULTURAL VALUES IN CONDITIONS OF ARMED CONFLICT
Relevance of the research. The phenomenon of war is one of the most profound and tragic themes in the philosophical reflection on human existence.
Svitlana Solianyk, Olena Nevmerzhytska
doaj +1 more source
Abstract In Property Rights: A Re-Examination, James Penner returns to and develops a project that he has been engaged in for nearly three decades: to replace the influential ‘bundle of rights’ picture of property, which he regards as irredeemably flawed, with an alternative account—one that regards property as a unified entitlement.
openaire +2 more sources
The Fredholm Property for Groupoids is a Local Property [PDF]
Fredholm Lie groupoids were introduced by Carvalho, Nistor and Qiao as a tool for the study of partial differential equations on open manifolds. This article extends the definition to the setting of locally compact groupoids and proves that \enquote{the Fredholm property is local}.
openaire +2 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Relevance of the research topic. The study of intrapersonal communication, in particular the conflict between the alter ego and the super ego of the subject, is extremely relevant in the context of modern socio-political and psychosocial conditions that ...
Olga Kyvliuk, Oleksandr Khlon
doaj +1 more source
On “P” property and the column-W property
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
PRIYADARSHAN, H, PILLAI, HK
openaire +3 more sources

