Results 51 to 60 of about 8,906,865 (345)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Property Values and Taxes in Southeastern Wisconsin [PDF]

open access: yes, 2009
County and municipal finance officials in Southeastern Wisconsin soon will receive word from the State of Wisconsin regarding 2009 property valuations within their jurisdictions.
Jeff Schmidt
core  

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Pitfalls of patenting and state authorization of medicines

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
During the lifecycle of a medicine - from its development to consumption - the developer has to go through several stages, such as obtaining the exclusive right for a medicine, obtaining permission to produce the medicine, obtaining permission to ...
V. I. Semenov   +2 more
doaj  

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Technology mapping: Leukemia Treatment

open access: yesRevista CENIC Ciencias Químicas, 2015
The increase in the incidence of various cancers has been one of the biggest challenges in the global public health for decades. Leukemia is a type of cancer that only in 2008 has affected 351,000 people of the world population.
Luciene Ferreira Gaspar Amaral   +2 more
doaj  

Privacy, Private Property and Collective Property [PDF]

open access: yesSSRN Electronic Journal, 2012
In A Theory of Justice John Rawls argued that people in a just society would have rights to some forms of personal property, whatever the best way to organise the economy. Without being explicit about it, he also seems to have believed that protection for at least some forms of privacy are included in the Basic Liberties, to which all are entitled ...
openaire   +5 more sources

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

The use of intellectual property right bundles and firm performance in China

open access: yesHumanities & Social Sciences Communications, 2023
Intellectual property rights (IPRs) have become increasingly important for firms in today’s knowledge-based economy, as evidenced by the strong growth in their use.
Li Zhang, Xiaoguang Shan
doaj   +1 more source

In Defense of Property [PDF]

open access: yes, 2008
This Article responds to an emerging view, in scholarship and popular society, that it is normatively undesirable to employ property law as a means of protecting indigenous cultural heritage. Recent critiques suggest that propertizing culture impedes the
Carpenter, Kristen A.   +2 more
core   +3 more sources

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