Results 71 to 80 of about 6,676,736 (296)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Mapping unobserved coopetitions between shopping malls using mobile geolocation data

open access: yesRegional Studies, Regional Science
This study challenges the conventional retail catchment analysis, which typically asserts that proximity is the primary driver of shopping mall patronage.
Yihan Guan   +2 more
doaj   +1 more source

Technological Monitoring Applied to Survey-Based on Brazilian Patent Applications about PEMFC

open access: yesJournal of Technology Management & Innovation, 2011
The present study aims to show the importance of patents as an instrument of technological innovation and to assess the relevance of technology of PEMFC in Brazil by means of the technological monitoring methodology from 1996 to 2005.
Deysimar de Souza Carvalho   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Sacks Forcing and the Shrink Wrapping Property

open access: yes, 2019
We consider a property stronger than the Sacks property, called the shrink wrapping property, which holds between the ground model and each Sacks forcing extension.
González, Osvaldo Guzmán   +1 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

The Compact Approximation Property does not imply the Approximation Property

open access: yes, 1992
It is shown how to construct, given a Banach space which does not have the approximation property, another Banach space which does not have the approximation property but which does have the compact approximation ...
Willis, George A.
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Antitrust, Innovation, and Uncertain Property Rights: Some Practical Considerations [PDF]

open access: yes, 2010
The intersection of antitrust and intellectual property circumscribes two century-long debates. The first pertains to questions about how antitrust law and intellectual property law interact, and the second pertains to questions about how parties can ...
Williamson, Dean V.
core   +1 more source

A property (T) for C*-algebras

open access: yes, 2005
We define a notion of Property (T) for an arbitrary $C^*$-algebra $A$ admitting a tracial state. We extend this to a notion of Property (T) for the pair $(A,B),$ where $B$ is a $C^*$-subalgebra of $A.$ Let $\Gamma$ be a discrete group and $C^*_r(\Gamma)$
Bekka, Bachir
core   +3 more sources

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