Results 71 to 80 of about 726,036 (269)

Handle number one links and Generalized Property $R$ [PDF]

open access: yesProceedings of the American Mathematical Society, 2012
It is shown that if the exterior of a link L in the three sphere admits a genus 2 Heegaard splitting, then L has Generalized Property R.
openaire   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Fractional (P,Q)-Total List Colorings of Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2013
Let r, s ∈ N, r ≥ s, and P and Q be two additive and hereditary graph properties. A (P,Q)-total (r, s)-coloring of a graph G = (V,E) is a coloring of the vertices and edges of G by s-element subsets of Zr such that for each color i, 0 ≤ i ≤ r − 1, the ...
Kemnitz Arnfried   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

On Property (A) and the socle of the $f$-ring $Frm(mathcal{P}(mathbb R), L)$ [PDF]

open access: yesCategories and General Algebraic Structures with Applications, 2018
For a frame $L$, consider the $f$-ring $ mathcal{F}_{mathcal P}L=Frm(mathcal{P}(mathbb R), L)$. In this paper, first we show that each minimal ideal of $ mathcal{F}_{mathcal P}L$ is a principal ideal generated by $f_a$, where $a$ is an atom of $L$.
Ali Asghar Estaji   +2 more
doaj  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

A study of novel telephone sequence spaces and some geometric properties

open access: yesJournal of Inequalities and Applications
For a nonnegative integer k, let T k $\mathcal {T}_{k}$ denote the kth telephone number. Consider the matrix T = ( T k r ) $\mathfrak{T}=(\mathfrak {T}_{kr})$ given by T k r = { r T r − 1 T k + 1 − 1 , 0 ≤ r ≤ k , 0 , r > k , $$\begin{aligned} \mathfrak {
Taja Yaying
doaj   +1 more source

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