Results 81 to 90 of about 726,036 (269)

Investigation of the Stability via Shadowing Property

open access: yesJournal of Inequalities and Applications, 2009
The shadowing property is to find an exact solution to an iterated map that remains close to an approximate solution. In this article, using shadowing property, we show the stability of the following equation in normed group: 4n−2Cn/2−1r2f(&
Sang-Hyuk Lee, Heejeong Koh, Se-Hyun Ku
doaj   +1 more source

Some differential-geometric properties of $R$-spaces

open access: yesTsukuba Journal of Mathematics, 2001
An \(R\)-space is the orbit \(Ad(K)a\) of a point \(a\) belonging to the unit hypersphere \(S\) of \(T_0(G/K)\), where \(G/K\) is an irreducible Riemannian symmetric space and \(Ad(K)\) the adjoint representation group. \(R\)-spaces form a large class of homogeneous Riemannian manifolds.
openaire   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

WordListsAnalytics: An R package for multiple data analysis of Property Listing Tasks

open access: yesSoftwareX
WordListsAnalytics allows sounder analyses of data collected in Property listing tasks, Semantic fluency tasks (SFT), and other related methods by calculating sample sizes to attain a specified coverage and estimating population parameters that ...
Cristobal Heredia   +3 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Management of Intellectual Property as a Generator of Resources in Mexican Higher Education Institutions

open access: yesMercados y Negocios
This paper was developed to analyze the level of implementation of intellectual property management processes in Higher Education Institutions (HEI).
Fernando Rodríguez   +2 more
doaj   +1 more source

On the Property N-1

open access: yesAbstract and Applied Analysis, 2016
We construct a continuous function f:[0,1]→R such that f possesses N-1-property, but f does not have approximate derivative on a set of full Lebesgue measure.
Stanisław Kowalczyk   +1 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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