Results 41 to 50 of about 3,455 (218)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

How Much is the Cathedral of St. Isaac of Dalmatia and Why a Struggle for Possession of the Property?

open access: yesУправленческое консультирование, 2018
The article discusses main problems of of preservation of cultural heritage of St. Petersburg included in the List of monuments of federal significance, that guard UN programs.
Alexander Nickolaevich Tsatsulin   +1 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

On some aspects of economic and legal regulation of Church property during the period of Soviet State foundation and development

open access: yesStudia Humanitatis, 2020
The article analyses the regulation of property relations between religious organizations and the Soviet government. Immediately after the establishment of Soviet power all the property of religious organizations was nationalized.
Maryin Evgeniy Vladimirovich
doaj  

Allocation of Demersal Harvest Rights in Iceland

open access: yesArctic Review on Law and Politics, 2010
It is generally understood that since 1984 the Icelandic fishery man- agement system has been based on individual transferable quotas (ITQs), that licenses for commercial fishing in Iceland were allocated to owners of vessels according to their fishing ...
Helgi Gretarsson
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

PROPERTY RESTITUTION IN ROMANIA [PDF]

open access: yesGlobal Economic Observer, 2014
The property right is one of the most important right of a person in modern societies. Most of the national legislations consists of complex provision in what comes to protect this right.
ALEXANDRU- CRISTIAN ROSU
doaj  

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