Results 51 to 60 of about 3,489,013 (348)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Fairness, Efficiency and Insider Trading: Deconstructing the Coin of the Realm in the Information Age [PDF]

open access: yes, 2001
Whether and how the federal securities laws should restrict insider trading is one of the most hotly debated topics in the securities law literature.
Kimberly D. Krawiec   +8 more
core   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

How Much is the Cathedral of St. Isaac of Dalmatia and Why a Struggle for Possession of the Property?

open access: yesУправленческое консультирование, 2018
The article discusses main problems of of preservation of cultural heritage of St. Petersburg included in the List of monuments of federal significance, that guard UN programs.
Alexander Nickolaevich Tsatsulin   +1 more
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

From Author's Right to Property Right [PDF]

open access: yesUniversity of Toronto Law Journal, 2012
Though copyright is usually categorized as a property right, efforts to justify copyright on other grounds have persisted since the eighteenth century. The Lockean defence, based on the author's labour, is usually seen as conducive to a property right but is sometimes linked instead (or in addition) to a personality right.
openaire   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

On some aspects of economic and legal regulation of Church property during the period of Soviet State foundation and development

open access: yesStudia Humanitatis, 2020
The article analyses the regulation of property relations between religious organizations and the Soviet government. Immediately after the establishment of Soviet power all the property of religious organizations was nationalized.
Maryin Evgeniy Vladimirovich
doaj  

Allocation of Demersal Harvest Rights in Iceland

open access: yesArctic Review on Law and Politics, 2010
It is generally understood that since 1984 the Icelandic fishery man- agement system has been based on individual transferable quotas (ITQs), that licenses for commercial fishing in Iceland were allocated to owners of vessels according to their fishing ...
Helgi Gretarsson
doaj   +1 more source

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