Results 71 to 80 of about 3,463,553 (284)
Under the modern economic relations the real estate construction became massive, which caused problems with involving the suspended construction objects into the civil circulation.
Z. K. Sabirova
doaj
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
¿Y el título para cuándo? El proceso de regularización del barrio Virgen Misionera
Resumen Este artículo presenta resultados preliminares de un trabajo de investigación en curso sobre políticas habitacionales y urbanas en San Carlos de Bariloche.
Tomás Alejandro Guevara
doaj +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The article in devoted to the content of property right, the triad of proprietor’s authorities, and analysis of differences in interpretation of property right by different states.
M. G. Krasnova
doaj
A Model of the Origins of Basic Property Rights [PDF]
This paper studies the origins of one of the most basic of property rights, namely, the right of an individual or an organization to the fruits of its labour.
A. Muthoo
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Government Property and Government Speech [PDF]
The relationship between property and speech is close but complicated. Speakers use places and things to deliver their messages, and rely on property rights both to protect expressive acts and to serve as an independent means of expression.
Blocher, Joseph
core +1 more source

