Results 101 to 110 of about 3,508,117 (344)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The Determinants of Property Rights In U.S. Marine Fisheries [PDF]

open access: yes
Using a sample of fisheries managed under the Magnuson Act, a probit model of the probability of property rights adoption is estimated. The probability of adoption increases as ex–vessel revenue increases and as proxies for transaction costs decrease ...
Joel Kincaid
core  

Family involvement in medical decision-making: examining the applicability of the legal framework in Flemish general practice through a vignette survey

open access: yesBMC Medical Ethics
Background Despite increasing attention to the involvement of family members or informal caregivers in patient care, their role remains underdeveloped in medical decision-making (MDM) models implemented in clinical practice.
Flore Vermijs   +7 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

On the Dual Nature of Weak Property Rights [PDF]

open access: yes
In the natural resource literature, convertional wisdom holds that weak property rights will cause a resource to be over-exploited. This is because weak property rights are typically perceived as a problem of input exclusion.
Douglas Wills   +2 more
core  

Collective action and property rights for sustainable development

open access: yes, 2021
Institutions for collective action and systems of property rights shape how people use natural resources. These patterns of use in turn affect the outcomes of people’s agricultural production systems.
CGIAR Program on Collective Action and Property Rights (CAPRi)
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

"Who's the thief?": Asymmetric Information and the Creation of Property Rights [PDF]

open access: yes
This paper studies the creation of property rights in a state of anarchy and in the presence of uncertainty about a potential appropriator's ability. In a game of conflict, securing property can be achieved by spending resources for protection.
Dana Sisak, Philipp Denter
core  

Property Rights in Light of the Economic Sanctions Imposed on Russia by Europe and the United States

open access: yesWorld Review of Political Economy
The arbitrary sanctioning of Russia by Europe and the United States in the context of the Russia–Ukraine war does not correspond to the definition of property rights as an aspect of juridical rights, and nor does the definition of proprietary rights or ...
Bin Yu
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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