Results 111 to 120 of about 3,698,026 (314)

How does property rights intensity affect rental arrangements in farmland transfer contracts? A dual perspective on property rights security and perception

open access: yesFrontiers in Sustainable Food Systems
IntroductionRational rental arrangements are essential for market-oriented farmland transfer and safeguard farmers’ land property income. Property rights intensity fundamentally determines land residual claim allocation and shapes farmland rental ...
Hanning Li   +3 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

"Who's the thief?": Asymmetric Information and the Creation of Property Rights [PDF]

open access: yes
This paper studies the creation of property rights in a state of anarchy and in the presence of uncertainty about a potential appropriator's ability. In a game of conflict, securing property can be achieved by spending resources for protection.
Dana Sisak, Philipp Denter
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Office Decentralization and Functional Obsolescence After COVID-19: Empirical Evidence from Hong Kong

open access: yesUrban Science
The COVID-19 pandemic, particularly during its declared Public Health Emergency of International Concern (PHEIC) period, has flattened the bid-rent curve and increased the rate of functional obsolescence of older office buildings.
Ervi Liusman, Kwong Wing Chau
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Optimal Property Rights in Financial Contracting [PDF]

open access: yes
In this paper we propose a theory of optimal property rights in a financial contracting setting. Following recent contributions in the property law literature, we emphasize the distinction between contractual rights, that are only enforceable against the
Kenneth Ayotte, Patrick Bolton
core  

Insurance in the field of intellectual property as an element of the mechanism of protection of these rights: a general overview

open access: yesТеорія і практика інтелектуальної власності
The renewal of insurance legislation, which coincided with revolutionary changes in digital technologies, influenced the emergence of new opportunities for the creation and use of intellectual property rights objects and increased the risks of violation
Olena Shtefan
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

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