Results 61 to 70 of about 403,714 (266)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
An innovative tester system for measuring mechanical property of foundry molding sand [PDF]
China Foundry, 2004 A new intelligent tester system for measuring multiple mechanical properties of foundry molding sand is introduced and has been patented for the invention in China.
Zuxi XIE, Qingchun XIANG, Xu WANG
doaj
SP creep properties of Gr.91 boiler pipings service-exposed in different USC power plants
Ubiquity Proceedings, 2018 The small punch (SP) testing technique was applied to five heats of Gr.91 steel, which had been actually used for boiler pipings in different USC power plants for long periods of time to investigate the applicability of this technique to the assessment ...
S. Komazaki +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Comfort Properties of Two Differential-Shrinkage Polyester Warp Knitted Fabrics
AUTEX Research Journal, 2016 Single-layered warp knitted fabrics were produced by the 60D/36F (containing 36 filaments) polyester yarn with differential shrinkage (DS) property in this study.
Chen Qing +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Note: The Smallest Nonevasive Graph Property
Discussiones Mathematicae Graph Theory, 2014 A property of n-vertex graphs is called evasive if every algorithm testing this property by asking questions of the form “is there an edge between vertices u and v” requires, in the worst case, to ask about all pairs of vertices.
Adamaszek Michał
doaj +1 more source
Chinese Journal of Magnetic Resonance, 2019 During in-situ exploitation of the oil shale, the connectivity of the pore structure of the reservoir directly affects not only the flow behavior and heat transfer efficiency of the heat-carrying medium, but also the diffusion and flow behaviors of the ...
LIU Zhi-jun +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source