Scientific Reports, 2023 Actinobacteria represent one of the largest bacterial phyla harboring many species of high medical, biotechnological and ecological relevance. Prophage elements are major contributors to bacterial genome diversity and were shown to significantly shape ...
Vikas Sharma +3 more
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Prophage Activation in the Intestine: Insights Into Functions and Possible Applications
Frontiers in Microbiology, 2021 Prophage activation in intestinal environments has been frequently reported to affect host adaptability, pathogen virulence, gut bacterial community composition, and intestinal health.
Jie Hu +4 more
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Common Oral Medications Lead to Prophage Induction in Bacterial Isolates from the Human Gut
Viruses, 2021 Many bacteria carry bacteriophages (bacterial viruses) integrated in their genomes in the form of prophages, which replicate passively alongside their bacterial host.
Steven G. Sutcliffe +3 more
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Gut MicrobesProphages can have major clinical implications through their ability to change pathogenic bacterial traits. There is limited understanding of the prophage role in ecological, evolutionary, adaptive processes and pathogenicity of Helicobacter pylori, a ...
Filipa F. Vale +4 more
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Msphere, 2021 Although we believe phages play an important role in horizontal gene transfer in exchanging genetic material, we do not know the distribution of the antimicrobial resistance (AMR) and/or virulence factor (VF) genes in prophages.
Kohei Kondo +2 more
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Prophage-dependent neighbor predation fosters horizontal gene transfer by natural transformation [PDF]
Msphere, 2020 Prophages are nearly ubiquitous in bacterial species. These integrated phage elements have previously been implicated in horizontal gene transfer (HGT) largely through their ability to carry out transduction (generalized or specialized).
Roberto C. Molina-Quiroz +4 more
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Control of lysogeny and antiphage defense by a prophage-encoded kinase-phosphatase module
Nature CommunicationsThe filamentous ‘Pf’ bacteriophages of Pseudomonas aeruginosa play roles in biofilm formation and virulence, but mechanisms governing Pf prophage activation in biofilms are unclear.
Yunxue Guo +17 more
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Timely excision of prophage Φ13 is essential for the Staphylococcus aureus infectious process [PDF]
Infection and ImmunityMobile genetic elements play an essential part in the infectious process of major pathogens, yet the role of prophage dynamics in Staphylococcus aureus pathogenesis is still not well understood.
Olivier Poupel +5 more
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Genomic footprint of a shared Type 5 prophage in “Candidatus Liberibacter asiaticus” and “Candidatus Liberibacter africanus,” two destructive bacterial pathogens of citrus Huanglongbing [PDF]
Applied and Environmental MicrobiologyHuanglongbing (HLB) is a bacterial disease that affects citrus trees and is considered the most severe citrus disease in the world. The three HLB-associated “Ca.
Frédéric Labbé +6 more
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A φSa3int (NM3) Prophage Domestication in Staphylococcus aureus Leads to Increased Virulence Through Human Immune Evasion [PDF]
MedCommStaphylococcus aureus with varying virulence is often isolated from chronic rhinosinusitis (CRS) patients and impacts disease severity. Prophage‐mediated virulence, particularly encoded by φSa3int (NM3) prophages, which often encodes human immune‐evasion
Roshan Nepal +9 more
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