Results 11 to 20 of about 18,160 (174)
DNA sequence heterogeneity of Campylobacter jejuni CJIE4 prophages and expression of prophage genes. [PDF]
PLoS ONE, 2014 Campylobacter jejuni carry temperate bacteriophages that can affect the biology or virulence of the host bacterium. Known effects include genomic rearrangements and resistance to DNA transformation. C. jejuni prophage CJIE1 shows sequence variability and
Clifford G Clark +5 more
doaj +4 more sources
PLoS Pathogens, 2009 Bacteriophages are major genetic factors promoting horizontal gene transfer (HGT) between bacteria. Their roles in dynamic bacterial genome evolution have been increasingly highlighted by the fact that many sequenced bacterial genomes contain multiple ...
Md Asadulghani +7 more
doaj +4 more sources
Deciphering active prophages from metagenomes [PDF]
mSystems, 2021 ABSTRACTTemperate phages (prophages) are ubiquitous in nature and persist as dormant components of host cells (lysogenic stage) before activating and lysing the host (lytic stage). Actively replicating prophages contribute to central community processes, such as enabling bacterial virulence, manipulating biogeochemical cycling, and driving microbial ...
Kristopher Kieft, Karthik Anantharaman
openaire +3 more sources
Microbiology and Molecular Biology Reviews, 2003 SUMMARY The majority of the bacterial genome sequences deposited in the National Center for Biotechnology Information database contain prophage sequences. Analysis of the prophages suggested that after being integrated into bacterial genomes, they undergo a complex decay process consisting of inactivating point mutations ...
Carlos, Canchaya +4 more
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Prophage Hunter: an integrative hunting tool for active prophages [PDF]
Nucleic Acids Research, 2019 Abstract Identifying active prophages is critical for studying coevolution of phage and bacteria, investigating phage physiology and biochemistry, and engineering designer phages for diverse applications. We present Prophage Hunter, a tool aimed at hunting for active prophages from whole genome assembly of bacteria.
Wenchen Song +14 more
openaire +2 more sources
CRISPR-Cas Controls Cryptic Prophages [PDF]
International Journal of Molecular Sciences, 2021 The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages.
Sooyeon Song +6 more
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Identification of novel prophage regions in Xenorhabdus nematophila genome and gene expression analysis during phage-like particle induction [PDF]
PeerJ, 2022 Background Entomopathogenic Xenorhabdus bacteria are endosymbionts of Steinernema nematodes and together they form an insecticidal mutualistic association that infects a wide range of insect species. Xenorhabdus produce an arsenal of toxins and secondary
Emilie Lefoulon +2 more
doaj +2 more sources
An Efficient, Counter-Selection-Based Method for Prophage Curing in Pseudomonas aeruginosa Strains
Viruses, 2021 Prophages are bacteriophages in the lysogenic state, where the viral genome is inserted within the bacterial chromosome. They contribute to strain genetic variability and can influence bacterial phenotypes. Prophages are highly abundant among the strains
Esther Shmidov +5 more
doaj +1 more source
Targeted Curing of All Lysogenic Bacteriophage from Streptococcus pyogenes Using a Novel Counter-selection Technique. [PDF]
PLoS ONE, 2016 Streptococcus pyogenes is a human commensal and a bacterial pathogen responsible for a wide variety of human diseases differing in symptoms, severity, and tissue tropism. The completed genome sequences of >37 strains of S.
Chad W Euler +5 more
doaj +1 more source
Evaluation of WGS-subtyping methods for epidemiological surveillance of foodborne salmonellosis [PDF]
, 2020 Background: Salmonellosis is one of the most common foodborne diseases worldwide. Although human infection by non-typhoidal Salmonella (NTS) enterica subspecies enterica is associated primarily with a self-limiting diarrhoeal illness, invasive bacterial ...
Mohammed, M. +3 more
core +1 more source