Results 11 to 20 of about 39,319 (207)

DNA sequence heterogeneity of Campylobacter jejuni CJIE4 prophages and expression of prophage genes. [PDF]

PLoS ONE, 2014
Campylobacter jejuni carry temperate bacteriophages that can affect the biology or virulence of the host bacterium. Known effects include genomic rearrangements and resistance to DNA transformation. C. jejuni prophage CJIE1 shows sequence variability and
Clifford G Clark, Patrick M Chong, Stuart J McCorrister, Philip Mabon, Matthew Walker, Garrett R Westmacott   +5 more
doaj   +4 more sources

The defective prophage pool of Escherichia coli O157: prophage-prophage interactions potentiate horizontal transfer of virulence determinants.

PLoS Pathogens, 2009
Bacteriophages are major genetic factors promoting horizontal gene transfer (HGT) between bacteria. Their roles in dynamic bacterial genome evolution have been increasingly highlighted by the fact that many sequenced bacterial genomes contain multiple ...
Md Asadulghani, Yoshitoshi Ogura, Tadasuke Ooka, Takehiko Itoh, Akira Sawaguchi, Atsushi Iguchi, Keisuke Nakayama, Tetsuya Hayashi   +7 more
doaj   +4 more sources

Deciphering active prophages from metagenomes [PDF]

mSystems, 2021
ABSTRACTTemperate phages (prophages) are ubiquitous in nature and persist as dormant components of host cells (lysogenic stage) before activating and lysing the host (lytic stage). Actively replicating prophages contribute to central community processes, such as enabling bacterial virulence, manipulating biogeochemical cycling, and driving microbial ...
Kristopher Kieft, Karthik Anantharaman
openaire   +3 more sources

Prophage Genomics [PDF]

Microbiology and Molecular Biology Reviews, 2003
SUMMARY The majority of the bacterial genome sequences deposited in the National Center for Biotechnology Information database contain prophage sequences. Analysis of the prophages suggested that after being integrated into bacterial genomes, they undergo a complex decay process consisting of inactivating point mutations ...
Carlos, Canchaya, Caroline, Proux, Ghislain, Fournous, Anne, Bruttin, Harald, Brüssow   +4 more
openaire   +3 more sources

Prophage Hunter: an integrative hunting tool for active prophages [PDF]

Nucleic Acids Research, 2019
Abstract Identifying active prophages is critical for studying coevolution of phage and bacteria, investigating phage physiology and biochemistry, and engineering designer phages for diverse applications. We present Prophage Hunter, a tool aimed at hunting for active prophages from whole genome assembly of bacteria.
Wenchen Song, Hai-Xi Sun, Carolyn Zhang, Li Cheng, Ye Peng, Ziqing Deng, Dan Wang, Yun Wang, Ming Hu, Wenen Liu, Huanming Yang, Yue Shen, Junhua Li, Lingchong You, Minfeng Xiao   +14 more
openaire   +2 more sources

CRISPR-Cas Controls Cryptic Prophages [PDF]

International Journal of Molecular Sciences, 2021
The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages.
Sooyeon Song, Ekaterina Semenova, Konstantin Severinov, Laura Fernández-García, Michael J. Benedik, Toshinari Maeda, Thomas K. Wood   +6 more
openaire   +2 more sources

An Efficient, Counter-Selection-Based Method for Prophage Curing in Pseudomonas aeruginosa Strains

Viruses, 2021
Prophages are bacteriophages in the lysogenic state, where the viral genome is inserted within the bacterial chromosome. They contribute to strain genetic variability and can influence bacterial phenotypes. Prophages are highly abundant among the strains
Esther Shmidov, Itzhak Zander, Ilana Lebenthal-Loinger, Sarit Karako-Lampert, Sivan Shoshani, Ehud Banin   +5 more
doaj   +1 more source

Targeted Curing of All Lysogenic Bacteriophage from Streptococcus pyogenes Using a Novel Counter-selection Technique. [PDF]

PLoS ONE, 2016
Streptococcus pyogenes is a human commensal and a bacterial pathogen responsible for a wide variety of human diseases differing in symptoms, severity, and tissue tropism. The completed genome sequences of >37 strains of S.
Chad W Euler, Barbara Juncosa, Patricia A Ryan, Douglas R Deutsch, W Michael McShan, Vincent A Fischetti   +5 more
doaj   +1 more source

Phage inducible islands in the gram-positive cocci [PDF]

, 2016
The SaPIs are a cohesive subfamily of extremely common phage-inducible chromosomal islands (PICIs) that reside quiescently at specific att sites in the staphylococcal chromosome and are induced by helper phages to excise and replicate.
A Bolotin, A Chopin, A Ruzin, B Frígols, BA Duerkop, C Ubeda, C Ubeda, C Ubeda, C Ubeda, C Ubeda, CH O'Callaghan, CM Hamilton, D Straume, D Viana, Davida Smyth, E Charpentier, E Maiques, G Ram, G Ram, Geeta Ram, IT Paulsen, J Chen, J Chen, J Chen, J Scott, J Scott, J-P Claverys, JA Lindsay, John Chen, José R Penadés, JR Penadés, M Kanehisa, MA Tormo, MD Ferrer, Miguel Martí, MÁ Tormo-Más, MÁ Tormo-Más, N Carpena, N Quiles-Puchalt, N Quiles-Puchalt, Nuria Quiles-Puchalt, RC Matos, Richard P Novick, Roser Martínez-Rubio, RP Novick, RP Novick, Suzanne Humphrey, SV Nguyen   +47 more
core   +1 more source

Characterization and Comparison of 2 Distinct Epidemic Community-Associated Methicillin-Resistant Staphylococcus aureus Clones of ST59 Lineage. [PDF]

, 2013
Sequence type (ST) 59 is an epidemic lineage of community-associated (CA) methicillin-resistant Staphylococcus aureus (MRSA) isolates. Taiwanese CA-MRSA isolates belong to ST59 and can be grouped into 2 distinct clones, a virulent Taiwan clone and a ...
A Bera, A Holmes, AE Fossum, AM Milstone, B Loffler, BA Diep, BE Gonzalez, BE Gonzalez, C Goerke, C Weidenmaier, Chih-Jung Chen, CJ Chen, CJ Chen, CJ Chen, CJ Chen, CJC de Haas, Clemens Unger, CP Montgomery, dS Aires, FC Tenover, FJ Chen, Friedrich Götz, GM Pupo, GW Coombs, J Bubeck Wardenburg, J Bubeck Wardenburg, J Kaneko, JM Voyich, Jodi A. Lindsay, K Georgiades, KB Kiser, LY Hsu, M Labandeira-Rey, M Otto, MR Mulvey, MZ David, N Zetola, Paul J. Planet, PE Fournier, PL Ho, R Wang, S Herbert, SHM Rooijakkers, SL Kaplan, T Jin, T Jin, V Merhej, WJ Wannet, WJB van Wamel, Wolfgang Hoffmann, Y Gillet, YC Huang, YC Huang, YC Huang, YC Huang, Yhu-Chering Huang   +55 more
core   +11 more sources