Prophage Hunter: an integrative hunting tool for active prophages [PDF]
Nucleic Acids Research, 2019 Identifying active prophages is critical for studying coevolution of phage and bacteria, investigating phage physiology and biochemistry, and engineering designer phages for diverse applications.
Wenchen Song +14 more
semanticscholar +3 more sources
The defective prophage pool of Escherichia coli O157: prophage-prophage interactions potentiate horizontal transfer of virulence determinants. [PDF]
PLoS Pathogens, 2009 Bacteriophages are major genetic factors promoting horizontal gene transfer (HGT) between bacteria. Their roles in dynamic bacterial genome evolution have been increasingly highlighted by the fact that many sequenced bacterial genomes contain multiple ...
Md Asadulghani +7 more
doaj +4 more sources
DNA sequence heterogeneity of Campylobacter jejuni CJIE4 prophages and expression of prophage genes. [PDF]
PLoS ONE, 2014 Campylobacter jejuni carry temperate bacteriophages that can affect the biology or virulence of the host bacterium. Known effects include genomic rearrangements and resistance to DNA transformation. C. jejuni prophage CJIE1 shows sequence variability and
Clifford G Clark +5 more
doaj +4 more sources
Prophage Tracer: precisely tracing prophages in prokaryotic genomes using overlapping split-read alignment [PDF]
Nucleic Acids Research, 2021 The life cycle of temperate phages includes a lysogenic cycle stage when the phage integrates into the host genome and becomes a prophage. However, the identification of prophages that are highly divergent from known phages remains challenging.
Kaihao Tang +6 more
semanticscholar +3 more sources
High-throughput screening reveals diverse lambdoid prophage inducers [PDF]
Microbiology SpectrumProphages, dormant bacteriophage genomes integrated within the bacterial chromosome, play pivotal roles in shaping microbial communities when awakened. Our current understanding of prophage activation is largely shaped by a narrow set of traditional DNA ...
Gayatri Nair +2 more
doaj +2 more sources
TisB enables antibiotic tolerance in Salmonella by preventing prophage induction through ATP depletion. [PDF]
PLoS PathogensPersisters are phenotypically antibiotic-tolerant cells which can survive antibiotic exposure without acquiring antibiotic resistance. A proposed important factor in persistence is low intracellular ATP levels, which are thought to reduce the activity of
Sebastian Braetz +5 more
doaj +2 more sources
PHAST, PHASTER and PHASTEST: Tools for finding prophage in bacterial genomes [PDF]
Briefings Bioinform., 2017 David Arndt +3 more
openalex +2 more sources
Deciphering active prophages from metagenomes [PDF]
mSystems, 2021 ABSTRACTTemperate phages (prophages) are ubiquitous in nature and persist as dormant components of host cells (lysogenic stage) before activating and lysing the host (lytic stage). Actively replicating prophages contribute to central community processes, such as enabling bacterial virulence, manipulating biogeochemical cycling, and driving microbial ...
Kristopher Kieft, Karthik Anantharaman
openaire +3 more sources
The bacterial toxin colibactin triggers prophage induction
Nature, 2022 Colibactin is a chemically unstable small-molecule genotoxin that is produced by several different bacteria, including members of the human gut microbiome1,2.
Justin E. Silpe +4 more
semanticscholar +1 more source
Prophage Typing of Staphylococcus aureus Strains Isolated from Broiler Poultry [PDF]
Archives of Razi Institute, 2021 Staphylococcus aureus is a well-known commensal and pathogen agent of many wild and domestic animals. A wide variety of infections can be caused by S. aureus, from suppurative skin infections to life-threatening septicemia.
Kh Rostami, M Nemati, F Pourahmad
doaj +1 more source