Results 71 to 80 of about 540,928 (304)

Will I? won't I? Why do men who have sex with men present for post-exposure prophylaxis for sexual exposures? [PDF]

, 2008
Background: Failures of post-exposure prophylaxis following sexual exposure (PEPSE) to prevent seroconversion have been reported and are often associated with ongoing risk exposure.
Fisher, M, Llewellyn, Carrie, Nambiar, K, Nixon, E, Perry, N, Richardson, D, Sayer, C   +6 more
core   +2 more sources

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

Some Peculiarities in the Dose Dependence of Separate and Combined In Vitro Cardiotoxicity Effects Induced by CdS and PbS Nanoparticles With Special Attention to Hormesis Manifestations

Dose-Response, 2020
Spherical nanoparticles (NPs) of cadmium and lead sulfides (diameter 37 ± 5 and 24 ± 4 nm, respectively) have been found to be cytotoxic for HL-1 cardiomyocytes as evidenced by decrease in adenosine triphosphate–dependent luminescence.
Vladimir Panov, Ilzira Minigalieva, Tatiana Bushueva, Eleonore Fröhlich, Claudia Meindl, Markus Absenger-Novak, Vladimir Shur, Ekaterina Shishkina, Vladimir Gurvich, Larisa Privalova, Boris A. Katsnelson   +10 more
doaj   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Surveying Kerman’s Afazalipour Hospital clinical and educational staff`s points of view about the clinical decision support system designed for reducing the possibility of pulmonary embolism and deep vein thrombosis

بیمارستان, 2013
Background: This research aims to design and implement a software with the ability to identify patients who are facing the risk of pulmonary embolism and deep venous thrombosis instantly as well as the ability to send timely reminders for any ...
Zh Agharezaei, SH Tofighi Sh, A Nemati, L AAgharezaei, K Bahaadinbeigi   +4 more
doaj  

Machine Learning-Empowered FTIR Spectroscopy Serum Analysis Stratifies Healthy, Allergic, and SIT-Treated Mice and Humans

Biomolecules, 2020
The unabated global increase of allergic patients leads to an unmet need for rapid and inexpensive tools for the diagnosis of allergies and for monitoring the outcome of allergen-specific immunotherapy (SIT).
Elke Korb, Murat Bağcıoğlu, Erika Garner-Spitzer, Ursula Wiedermann, Monika Ehling-Schulz, Irma Schabussova   +5 more
doaj   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria [PDF]

, 2015
BACKGROUND Sporozoite immunization of animals and humans under a chemo-prophylactic cover of chloroquine (CPS-CQ) efficiently induces sterile protection against malaria.
Bijker, Else M, Cockburn, Ian, Nganou-Makamdop, Krystelle, Sauerwein, Robert W, van Gemert, Geert-Jan, Zavala, Fidel   +5 more
core   +2 more sources

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

Advanced Functional Materials, EarlyView.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee, Inhoo Choi, Anara Molkenova, Yengwoo Son, Seungmin Yang, Mina Kwon, Tae‐Im Kim, Ki Su Kim, Sei Kwang Hahn   +8 more
wiley   +1 more source

EPIDEMIC SITUATION FOR HIV-INFECTION IN SIBERIAN FEDERAL REGION IN 2014

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Analyze main epidemiologic indicators for HIV-infection on the territory of SFR for the period from 2012 to 2014 with allotment of contributions of regions into the epidemic for development of personalized regional program for further containment of
E. S. Dovgopolyuk, L. V. Puzyreva, A. D. Safonov, A. V. Mordyk, A. T. Tyumentsev, L. I. Levakhina, G. A. Kalacheva   +6 more
doaj   +1 more source