Objective Polymyalgia rheumatica (PMR) is a common indication for long‐term glucocorticoid (GC) treatment. Bone‐protective and gastroprotective medications are recommended for those at high risk of adverse events from GCs, but no trials have evaluated their effectiveness in PMR.
Helen Twohig +5 more
wiley +1 more source
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek +18 more
wiley +1 more source
Cytomegalovirus prophylaxis using low-dose and ultra-low-dose valganciclovir for patients who have undergone allogeneic hematopoietic stem cell transplantation: A retrospective study. [PDF]
Tseng WH +4 more
europepmc +1 more source
A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun +13 more
wiley +1 more source
ANK1 and EPB41 Variants and the Risk of Steroid‐Induced Osteonecrosis
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen +21 more
wiley +1 more source
Antimicrobial prophylaxis in colorectal surgery: focus on ertapenem
Fausto de LallaLibero Docente of Infectious Diseases, University of Milano, Milano, ItalyAbstract: Despite improvement in infection control measures and surgical practice, surgical site infections (SSIs) remain a major cause of morbidity and mortality ...
Fausto de Lalla
core
Biologic Augmentation With Biocomposite Scaffold in Revision Quadriceps Tendon Repair
Abstract Quadriceps tendon rupture is a relatively uncommon injury, typically occurring in middle‐aged males, and is often associated with systemic comorbidities or trauma. Although primary repair techniques provide excellent outcomes when performed acutely, revision surgery presents unique challenges due to poor tissue quality and compromised ...
Cory N. Meixner +2 more
wiley +1 more source
Extended oral antibiotic prophylaxis does not reduce periprosthetic joint infection after primary outpatient total shoulder arthroplasty: A matched cohort analysis. [PDF]
Lauck BJ +6 more
europepmc +1 more source
Abstract Multiligamentous knee injuries involving anterior cruciate ligament rupture and lateral‐sided instability, including proximal tibiofibular joint instability and lateral collateral ligament deficiency, present unique challenges in restoring knee stability.
Ryan J. Froom +4 more
wiley +1 more source
Infectious complications after CAR T-cell therapy: mechanisms, risk stratification, and prevention. [PDF]
Lee E +7 more
europepmc +1 more source

