Results 201 to 210 of about 541,793 (303)

Concizumab in hemophilia with inhibitors: longer-term efficacy and safety results from the phase 3 explorer7 study. [PDF]

Blood Adv
Mahlangu J, Boban A, Bruzelius M, Castaman G, Hampton K, Knoebl P, Lebreton A, Linari S, López-Jaime FJ, Martins Mazini Tavares C, Nekkal MS, Nogami K, Rhode Høgh Nielsen A, Shapiro A, d'Oiron R.   +14 more
europepmc   +1 more source

Predicting FVIII Activity in Patients Who Use Recombinant FVIII Fc Fusion Protein for Prophylaxis and Treatment of Bleeding Episodes [PDF]

, 2014
Allen, G, Li, L, Mahlangu, JN, Pasi, J, Pierce, GF, Quon, DV, Shapiro, AD, Zhu, Y   +7 more
core  

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway, Cinzia Dello Russo, Nicholas Bass, Elvira Bramon, Helen Cross, Natalie Curley, Sarah Curran, Helen Davies, Jana De Villiers, William Evans, Bernhard Frank, Alice Groves, Judith Hayward, Jon Higham, Dyfrig A. Hughes, Shwe Sin Kyaw, Anthony G. Marson, Ailsa McLellan, Seth Mensah, Francis O'Neill, Jane Sargison, Sanjay M. Sisodiya, Jill Swan, Joanna M. Zakrewska, Munir Pirmohamed   +24 more
wiley   +1 more source

CMV Preventive and Treatment Studies in Children Undergoing Haematopoietic Stem Cell Transplant: A Systematic Review. [PDF]

Rev Med Virol
Fusani L, Fusco E, Fonseca M, Breuer J, Rao K, Galli L, Bamford A, Kadambari S.   +7 more
europepmc   +1 more source

PrEP at the site of action in cisgender and transgender women: A pharmacology study of blood and rectal CD4+ lymphocytes

British Journal of Clinical Pharmacology, EarlyView.
Background Female sex hormones used in feminizing hormone therapy (FHT) may influence activation and persistence of HIV pre‐exposure prophylaxis (PrEP) medications. The clinical relevance of this interaction remains unclear, particularly for transgender and cisgender women (TGW and CGW).
Elizabeth Hastie, Megha Srivasta, Edward R. Cachay, Leah Burke, Sara Gianella, Stephen Rawlings, Frank Z. Stanczyk, Craig Sykes, Angela D. M. Kashuba, Jill Blumenthal, Mackenzie L. Cottrell   +10 more
wiley   +1 more source

Comparing Efficacy and Safety of Itraconazole Solution Versus Posaconazole for Antifungal Prophylaxis After Heart Transplant. [PDF]

Open Forum Infect Dis
Tayyar R, Drucker D, Lee R, Le T, Teuteberg J, Khush K, Luikart H, Intrieri T, Moayedi Y, Alegria W, Dieringer T, Henricksen E, Subramanian A.   +12 more
europepmc   +1 more source

Real‐Time Monitoring of In Vitro Transcription for Production of mRNA Using Raman Spectroscopy

Biotechnology and Bioengineering, EarlyView.
Schematic depicting the workflow for model building and validation using Raman spectroscopy for real‐time monitoring of IVT. ABSTRACT The success of COVID‐19 mRNA vaccines showcased the transformative potential of this adaptable, plug‐and‐play, and rapid response platform.
Julia Puppin Chaves Fulber, Xingge Xu, Hadi El Radi, Kevin Grollier, Amine A. Kamen   +4 more
wiley   +1 more source

Multicentre, adaptive, double-blind, three-arm, placebo-controlled, non-inferiority trial examining antimicrobial prophylaxis duration in cardiac surgery (CALIPSO): trial protocol. [PDF]

BMJ Open
Peel T, McGiffin D, Smith J, Forbes A, Marasco S, Pilcher D, Stewardson AJ, Petrie D, Peleg AY, Wisniewski J, Forster S, Druce P, Roney J, Astbury S, Berkovic D, Mccracken P, Myles PS, CALIPSO Trial Steering Committee.   +17 more
europepmc   +1 more source

Beyond valganciclovir: A meta-analysis of letermovir's safety and efficacy in cytomegalovirus prophylaxis after solid organ transplantation. [PDF]

BMC Infect Dis
Usman M, Yuan Z, Yu H, Chen X, Tang Z, Liu C, Li Z, He W, Xu K.   +8 more
europepmc   +1 more source