Results 221 to 230 of about 540,753 (335)

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Extended thrombotic prophylaxis in COVID-19 early discharge: A retrospective cohort study. [PDF]

PLoS One
Van't Hoff ST, Helfrich G, Boerman S, Hardeman HA.   +3 more
europepmc   +1 more source

The Efficacy of Dextran-40 as a Venous Thromboembolism Prophylaxis Strategy in Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy [PDF]

, 2017
R. Sleightholm, D. Watley, S. Wahlmeier, A. Patel, J.M. Foster   +4 more
openalex   +1 more source

Low‐intervention clinical trials in Spain: Do they progress?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Low‐Intervention Clinical Trials (LICTs) are generally pragmatic trials that investigate medicinal products already authorized for use. In 2014, simplified regulatory frameworks were introduced for LICTs with the aim of reducing regulatory burden and operational complexity, to foster non‐commercial clinical trials (NCCTs); the mandatory ...
Claudia Erika Delgado‐Espinoza, Mayro J. Cortés Pestana, Kristopher Amaro, Rosa M. Antonijoan, Caridad Pontes   +4 more
wiley   +1 more source

Intimate Partner Violence Influences Women’s Engagement in the Early Stages of the HIV Pre-exposure Prophylaxis (PrEP) Care Continuum: Using Doubly Robust Estimation

, 2019
Tiara C. Willie, Danya E. Keene, Jamila K. Stockman, Kamila A. Alexander, Sarah K. Calabrese, Trace Kershaw   +5 more
openalex   +2 more sources

Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia.

New England Journal of Medicine, 2007
O. Cornely, J. Maertens, D. Winston, J. Perfect, A. Ullmann, T. Walsh, D. Helfgott, J. Hołowiecki, D. Stockelberg, Y. Goh, M. Petrini, C. Hardalo, R. Suresh, D. Angulo-Gonzalez   +13 more
semanticscholar   +1 more source

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Intrapartum antibiotic prophylaxis failure and group-B streptococcus early-onset disease

, 2011
Alberto Berardi, Licia Lugli, Cecilia Rossi, Mariachiara China, Claudio Chiossi, Lucia Gambini, Battista Guidi, Maria Federica Pedna, Marina Piepoli, Angela Simoni, Fabrizio Ferrari   +10 more
openalex   +2 more sources

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng, Zhong Hui Huang, Austen Worth, Claire Booth, Joseph F. Standing   +4 more
wiley   +1 more source

Venous Thromboembolism Risk Assessment and Prophylaxis in Trauma Patients. [PDF]

Int J Environ Res Public Health
Tanmit P, Singthong P, Angkasith P, Teeratakulpisarn P, Wongkonkitsin N, Prasertcharoensuk S, Thanapaisal C.   +6 more
europepmc   +1 more source