Results 161 to 170 of about 6,245 (267)

Vulval Lichen Sclerosus Associated With Immune Checkpoint Inhibitor Therapy: A Case Series of 11 Patients

Australasian Journal of Dermatology, EarlyView.
ABSTRACT There have only been a limited number of case reports that have described vulval lichen sclerosus in patients receiving immune checkpoint inhibitor (ICI) therapy. We describe 11 cases of vulval lichen sclerosus in patients with melanoma treated with ICIs, and in nine of these cases, the lichen sclerosus symptoms began after ICI commencement ...
Sophie Walter, Francesca Watts, Raquel Ruiz Araujo, Thevaki Wain, Amanda Glanz, Diona Damian, Matteo S. Carlino, Alexander M. Menzies, Georgina V. Long, Linda K. Martin   +9 more
wiley   +1 more source

Structural insights into heme-iron dependent N-N bond formation enzyme LnzB. [PDF]

Commun Chem
Huang H, Wang L, Chen P, Yang T, Zhu C, Li S, Zhou Y, Tan Y, Li Z, Zhang H, Chen J, Zhang ZM.   +11 more
europepmc   +1 more source

The natural polypropionate-derived esters of the mollusc Onchidium sp. [PDF]

, 1992
Debitus, Cécile, Riguera, R., Rodriguez, J.   +2 more
core  

Assessing General Practitioners' Confidence in Undertaking Assessment and Ongoing Management of Patients With Diagnosed, Stable Vulval Lichen Sclerosus (VLS): Laying the Foundation for a Shared‐Care Model

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background Vulval Lichen Sclerosus (VLS) is a chronic inflammatory condition requiring lifelong management to prevent severe complications including malignancy. A shared care model between general practitioners (GPs) and public non‐GP specialists (dermatologist or gynaecologist) for patients with stable LS would alleviate the demand on public ...
Arav Kannen, Carolyn Marlow, Suzanne Edwards, Arabella Wallett   +3 more
wiley   +1 more source

Severity of Hypoxia-Induced Effects on 3T3-L1 Adipocyte Secretory Function Is Attenuated Dose-Dependently by Individual Short-Chain Fatty Acids. [PDF]

Nutrients
Burns JL, Van K, Alzubi A, Cho CE, Monk JM.   +4 more
europepmc   +1 more source

β-Hydroxy Esters as Malonic Semialdehyde Proelectrophiles in Enantioselective Butadiene-Mediated Crotylation: Total Synthesis of Octalactins A and B. [PDF]

Org Lett
Wu J, Krische MJ.
europepmc   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

Emerging Therapeutics for Primary Biliary Cholangitis. [PDF]

Korean J Gastroenterol
Cho EJ.
europepmc   +1 more source

Sodium butyrate ameliorates renal tubular lipid accumulation through a protein phosphatase 2A/transcription factor EB axis in diabetic nephropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Extensive evidence indicates that lipid accumulation causes renal tubular injury, which further contributes to diabetic nephropathy (DN) progression. Short‐chain fatty acids (SCFAs) play an important role in the maintenance of cellular metabolic health.
Jiayin Tao, Sinan Ai, Yaoxian Wang, Yuning Liu, Jingwei Zhou, Qingqing Liu, Xu Wang, Danting Li, Xin Li, Lin Wang, Jinyi Hou, Liang Peng, Zhen Wang   +12 more
wiley   +1 more source

Intake of food additive preservatives and incidence of cancer: results from the NutriNet-Santé prospective cohort.

BMJ
Hasenböhler A, Javaux G, Payen de la Garanderie M, de Edelenyi FS, Yvroud-Hoyos P, Agaësse C, De Sa A, Huybrechts I, Pierre F, Audebert M, Coumoul X, Julia C, Kesse-Guyot E, Allès B, Deschamps V, Hercberg S, Chassaing B, Srour B, Deschasaux-Tanguy M, Touvier M.   +19 more
europepmc   +1 more source